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Efficacy and safety of World Health Organization group 5 drugs for multidrug-resistant tuberculosis treatment / Nicholas Winters (2015)
Titre : Efficacy and safety of World Health Organization group 5 drugs for multidrug-resistant tuberculosis treatment Type de document : document électronique Auteurs : Nicholas Winters, Auteur ; Guillaume Butler-Laporte, Auteur ; Dick Menzies, Auteur Editeur : European Respiratory Society (ERS) Année de publication : 2015 Collection : European Respiratory Journal num. 46 Importance : p.1461-1470 Langues : Anglais (eng) Catégories : [TUBER] traitement:résistance:multirésistance
[TUBER] traitement:traitement curatif:médicament spécial MDRIndex. décimale : TU 8.5.1. MDR (Multi Drug Resistance / XDR (X-treme Drug Resistance) En ligne : https://erj.ersjournals.com/content/46/5/1461 Format de la ressource électronique : HTML, PDF Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=9418 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : Electronic cigarette use in youths : a position statement of the Forum of International Respiratory Societies Type de document : document électronique Auteurs : Thomas W. Ferkol, Auteur ; Harold J. Farber, Auteur ; Stefania La Grutta, Auteur Editeur : European Respiratory Society (ERS) Année de publication : 2018 Collection : European Respiratory Journal Importance : 9 p. Langues : Anglais (eng) Catégories : [DIVERS] personne:famille:adolescent
[DIVERS] personne:famille:enfant
[TABAC] chimie du tabac:constituant:alcaloïde:nicotine
[TABAC] chimie du tabac:tabac fumé:cigarette:cigarette électronique
[TABAC] prévention:recommandation
[TABAC] tabagisme:effet du tabac:effet neurologiqueIndex. décimale : TA 1.1.1 Cigarettes (« normales », électroniques, aromatisées,…) Résumé : Children and adolescents are highly susceptible to nicotine addiction, which affects their brain development, even in those who smoke infrequently. Young people who become addicted to nicotine are at greater risk of becoming lifelong tobacco consumers. The use of nicotine-delivering electronic cigarettes has risen dramatically among youths worldwide. In addition to physical dependence, adolescents are susceptible to social and environmental influences to use electronic cigarettes. The product design, flavours, marketing, and perception of safety and acceptability have increased the appeal of electronic cigarettes to young people, thus leading to new generations addicted to nicotine. Moreover, there is growing evidence that electronic cigarettes in children and adolescents serve as a gateway to cigarette
smoking. There can be no argument for harm reduction in children. To protect this vulnerable population from electronic cigarettes and other nicotine delivery devices, we recommend that electronic cigarettes be regulated as tobacco products and included in smoke-free policies. Sale of electronic cigarettes should be
barred to youths worldwide. Flavouring should be prohibited in electronic cigarettes, and advertising accessible by youths and young adults be banned. Finally, we recommend greater research on the health effects of electronic cigarettes and surveillance of use across different countries.En ligne : https://doi.org/10.1183/13993003.00278-2018 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=9737 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
European Respiratory Society statement on novel nicotine and tobacco products, their role in tobacco control and “harm reduction” / Daniel Tzu-Hsuan Chen (2024)
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Exposure to second-hand smoke / M. Pérez-Rios (2007)
Titre : Exposure to second-hand smoke : a population-based survey in Spain Type de document : texte imprimé Auteurs : M. Pérez-Rios, Auteur ; M.I. Santiago-Pérez, Auteur ; B. Alonso, Auteur ; A. Malvar, Auteur Editeur : European Respiratory Society (ERS) Année de publication : 2007 Collection : European Respiratory Journal num. 29:4 Importance : p. 818-819 Langues : Anglais (eng) Catégories : [DIVERS] géographie:Europe:Europe méridionale:Espagne
[TABAC] étude:enquête
[TABAC] tabagisme:tabagisme passif:tabagisme environnementalIndex. décimale : TA 7.1 Généralités Résumé : Between December 2004 and January 2005, we developed a study on tobacco use and SHS exposure among the general population in the northern Spanish region of Galicia. The source of sampling was the regional healthcare card system, which covers 97% of the population. The study yielded SHS exposure data collected in Galicia, based on a representative population sample. Galicia is located in the north-west of Spain and was estimated to have a population of 2.7 million in 2004, with a smoking prevalence of 29% (95% confidence interval 27.8–30.2%). People who smoked daily or occasionally were classified as smokers. Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=8114 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité TA 005671 TA 7.1 PER E Article/Périodique Bibliothèque FARES Tabac Consultation sur place
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Genetic variation as a predictor of smoking cessation. A promising preventive and intervention tool for chronic respiratory diseases / M. Quaak (2009)
Titre : Genetic variation as a predictor of smoking cessation. A promising preventive and intervention tool for chronic respiratory diseases Type de document : texte imprimé Auteurs : M. Quaak, Auteur ; C.P. van Schayck, Auteur ; A.M. Knaapen, Auteur ; F.J. van Schooten, Auteur Editeur : European Respiratory Society (ERS) Année de publication : 2009 Collection : European Respiratory Journal num. 33 Importance : p. 468-480 Présentation : tab., ill. Langues : Anglais (eng) Catégories : [TABAC] sevrage tabagique
[TABAC] tabagisme:aspect psychologique:comportement:addiction:traitement des addictions
[TABAC] tabagisme:risque:facteur associé:génétiqueIndex. décimale : TA 4.1.1 Facteurs prédictifs du tabagisme (génétique inclus) Résumé : obacco smoking continues to be the largest preventable cause of premature morbidity and mortality throughout the world, including chronic respiratory diseases such as asthma and chronic obstructive pulmonary disease. Although most smokers are highly motivated to quit and many smoking cessation therapies are available, cessation rates remain very low.
Recent research strongly suggests that variation in genetic background is an important determinant of smoking behaviour and addiction. Since these genetic variants might also influence the response to smoking cessation pharmacotherapies, it is likely that assessment of genetic background could be a promising tool to guide selection of the most effective cessation treatment for an individual smoker. Recently, it has been shown that genetic variants in the dopaminergic system, opioid receptors, the bupropion-metabolising enzyme CYP2B6 and the nicotine-metabolising enzyme CYP2A6 may play an important role in predicting smoking cessation responses to nicotine replacement therapy and bupropion treatment. Despite the progress that has been made, several challenges will still have to be overcome before genetically tailored smoking cessation therapy can be implemented in standard clinical practice.En ligne : https://erj.ersjournals.com/content/33/3/468 Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=8070 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Home and workplace smoking bans in Italy, Ireland, Sweden, France and the Czech Republic / J.E. Heck (2010)
Titre : Home and workplace smoking bans in Italy, Ireland, Sweden, France and the Czech Republic Type de document : texte imprimé Auteurs : J.E. Heck, Auteur ; I. Stücker, Auteur ; Shane Allwright, Auteur ; E.R. Gritz, Auteur Editeur : European Respiratory Society (ERS) Année de publication : 2010 Collection : European Respiratory Journal num. 35:5 Importance : p. 969-979 Présentation : tab., graph. Langues : Anglais (eng) Catégories : [DIVERS] géographie:Europe:Europe du Nord:Suède
[DIVERS] géographie:Europe:Europe méridionale:Italie
[DIVERS] géographie:Europe:Europe occidentale:France
[DIVERS] géographie:Europe:Europe occidentale:Irlande
[DIVERS] personne:par sexe:femme:femme enceinte
[PROMOSAN] allergie:type d'allergie:allergie environnementale:habitation
[TABAC] étude
[TABAC] législation:législation antitabac:interdiction de fumer
[TABAC] législation:milieu réglementé:lieu de travail
[TABAC] tabagisme:tabagisme passifMots-clés : Tchéquie ou République tchèque Index. décimale : TA 9.3 Législation européenne et mondiale Résumé : The purpose of this study was to report predictors and prevalence of home and workplace smoking bans in five European countries. We conducted a population-based telephone survey of 4,977 females, ascertaining factors associated with smoking bans. Odds ratios and 95% confidence intervals were derived using unconditional logistic regression. A complete home smoking ban was reported by 59.5% of French, 63.5% of Irish, 61.3% of Italian, 74.4% of Czech and 87.0% of Swedish females. Home smoking bans were associated with younger age and being bothered by secondhand smoke, and among smokers, inversely associated with greater tobacco dependence. Among nonsmokers, bans were also related to believing smoking is harmful (OR 1.20, 95% CI 1.11-1.30) and having parents who smoke (OR 0.62, 95% CI 0.52-0.73). Workplace bans were reported by 92.6% of French, 96.5% of Irish, 77.9% of Italian, 79.1% of Czech and 88.1% of Swedish females. Workplace smoking bans were reported less often among those in technical positions (OR 0.64, 95% CI 0.50-0.82) and among skilled workers (OR 0.53, 95% CI 0.32-0.88) than among professional workers. Workplace smoking bans are in place for most workers in these countries. Having a home smoking ban was based on smoking behaviour, demographics, beliefs and personal preference. Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=8104 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité TA 005652 TA 9.3 HEC H Article/Périodique Bibliothèque FARES Tabac Consultation sur place
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Impact of acute exposure to tobacco smoke on gelatinases in the bronchoalveolar space / P. Glader (2008)
Titre : Impact of acute exposure to tobacco smoke on gelatinases in the bronchoalveolar space Type de document : texte imprimé Auteurs : P. Glader, Auteur ; B. Eldh, Auteur ; S. Bozinovski, Auteur ; K. Andelid, Auteur Editeur : European Respiratory Society (ERS) Année de publication : 2008 Collection : European Respiratory Journal num. 32 Importance : p.644-650 Présentation : tab., ill. Langues : Anglais (eng) Catégories : [TABAC] chimie du tabac:fumée
[TABAC] étude
[TABAC] tabagisme:effet du tabac
[TABAC] tabagisme:pathologie:pathologie respiratoire:broncho-pneumopathie chronique obstructiveIndex. décimale : TA 3.2.2.4 Pathologies respiratoires (sauf 3.2.2.1, 3.2.2.2, 3.2.2.3) Résumé : Clinical studies have indicated increased gelatinase activity in the airways of patients suffering from chronic obstructive pulmonary disease caused by tobacco smoke. The present study aimed to determine whether acute exposure to tobacco smoke per se causes a substantial and lasting impact on gelatinases and their inhibitors in the peripheral airways of atopic and nonatopic human subjects.
Bronchoscopy with bronchoalveolar lavage (BAL) was performed on occasional smokers with and without atopy before and after smoking 10 cigarettes over a 48-h period. Samples from a group of never-smokers not exposed to tobacco smoke served as controls. Gelatinase identity and activity were measured using zymography, and gelatinase activity assay and concentrations of matrix metalloproteinase (MMP)-2, MMP-9, tissue inhibitor of MMP (TIMP)-1 and TIMP-2 were measured using ELISA.
The results revealed no pronounced changes in identity, net activity or concentration of the gelatinases or changes in concentrations of TIMP-1 and TIMP-2 in BAL fluid before and after acute exposure to tobacco smoke.
In conclusion, the present experimental study indicates that acute exposure to tobacco smoke does not cause any substantial impact on gelatinases or their inhibitors in the peripheral airways, irrespective of atopy status, a finding that is compatible with the fact that it takes many years of tobacco smoking to establish chronic obstructive pulmonary disease.En ligne : https://erj.ersjournals.com/content/32/3/644 Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=8073 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : Implementing tuberculosis entry screening for asylum seekers : the Groningen experience Type de document : document électronique Auteurs : Onno W. Akkerman, Auteur Editeur : European Respiratory Society (ERS) Année de publication : 2016 Collection : European Respiratory Journal num. 48 Importance : p.261-264 Langues : Anglais (eng) Catégories : [DIVERS] géographie:Europe:Europe occidentale:Pays-Bas
[DIVERS] personne:migrantIndex. décimale : TU 3.6.b. Réfugiés / migrants En ligne : https://doi.org/10.1183/13993003.00112-2016 Format de la ressource électronique : HTML, PDF Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=9438 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Increased Rho-kinase expression and activity and pulmonary endothelial dysfunction in smokers with normal lung function / S. Duong-Quy (2011)
Titre : Increased Rho-kinase expression and activity and pulmonary endothelial dysfunction in smokers with normal lung function Type de document : texte imprimé Auteurs : S. Duong-Quy, Auteur ; P. Dao, Auteur ; C. Guilluy, Auteur ; P; Pacaud, Auteur Editeur : European Respiratory Society (ERS) Année de publication : 2011 Collection : European Respiratory Journal num. 37 Importance : p. 349-355 Présentation : tab., graph. ill. Langues : Anglais (eng) Catégories : [TABAC] étude
[TABAC] tabagisme:pathologie:pathologie respiratoireIndex. décimale : TA 3.2.2.4 Pathologies respiratoires (sauf 3.2.2.1, 3.2.2.2, 3.2.2.3) Résumé : Endothelial dysfunction is one of the main consequences of the toxic effects of cigarette smoke on the vascular system. Increasing evidence suggests that the small G-protein RhoA and its downstream effectors, the Rho-kinases (ROCKs), are involved in systemic endothelial dysfunction induced by cigarette smoke. This study aimed to evaluate the role of the RhoA/ROCKs pathway in pulmonary artery endothelial function in current smokers with normal lung function. Lung tissues were obtained from nonsmokers and smokers who underwent lobectomy for lung carcinoma. Arterial relaxation in response to acetylcholine (ACh) was assessed in isolated pulmonary arterial rings. Protein expressions and activities of endothelial nitric oxide synthase (eNOS), ROCKs and the myosin phosphatase subunit 1 (MYPT-1) were sought. Relaxation in response to ACh was significantly lower in smokers as compared with nonsmokers (n = 8 in each group), consistent with reduced eNOS activity in the former compared with the latter. eNOS protein expression remained, however, the same in both groups. Expression of ROCKs, guanosine triphosphate-RhoA and phosphorylated MYPT-1 were significantly increased in smokers compared with controls. Pulmonary endothelial dysfunction is present in smokers whose lung function has not yet been impaired. Reduced activity of eNOS accounts at least in part for this endothelial dysfunction. Increased expression and activity of ROCKs accounts for another part through direct or indirect inhibition of the Rho-A/ROCKs pathway on nitric oxide synthesis and sustained pulmonary vasoconstriction through inhibition of myosin phosphatase. En ligne : https://erj.ersjournals.com/content/37/2/349 Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=8059 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : Lifting the smokescreen Type de document : texte imprimé Auteurs : John Britton, Auteur ; F. Godfrey, Auteur Editeur : European Respiratory Society (ERS) Année de publication : 2006 Collection : European Respiratory Journal num. 27:5 Importance : p. 871-873 Langues : Anglais (eng) Catégories : [DIVERS] géographie:Europe
[TABAC] étude:statistique:morbidité
[TABAC] législation:législation antitabac
[TABAC] tabagisme:tabagisme passifIndex. décimale : TA 7.1 Généralités Résumé : Evidence on the health effects of exposure to second-hand tobacco smoke was first published in 1974 1. Since then, over 20 independent reports published by a range of organisations, ranging from the International Agency for Research on Cancer (IARC) 2, the Environmental Protection Agency (EPA) 3 and the German Maximale Arbeitsplatz Konzentration (MAK) Commission 4, have confirmed that exposure to second-hand smoke causes a range of chronic and fatal conditions, including ischaemic heart disease, stroke, lung cancer and chronic obstructive pulmonary disease. Whilst the magnitude of risk is small, the exposure of nonsmokers to second-hand smoke in Europe is widespread and, therefore, the potential harm is considerable. En ligne : http://erj.ersjournals.com/content/27/5/871?cited-by=yesl27/5/871 Format de la ressource électronique : HTML, PDF Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=8117 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité TA 005675 TA 7.1 BRI L Article/Périodique Bibliothèque FARES Tabac Consultation sur place
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Light-emitting diode fluorescence microscopy for tuberculosis diagnosis: a meta-analysis / Eva W. Chang (2016)
Titre : Light-emitting diode fluorescence microscopy for tuberculosis diagnosis: a meta-analysis Type de document : document électronique Auteurs : Eva W. Chang, Auteur ; Anne-Laure Page, Auteur ; Maryline Bonnet, Auteur Editeur : European Respiratory Society (ERS) Année de publication : 2016 Collection : European Respiratory Journal num. 47 Importance : p.929-937 Langues : Anglais (eng) Catégories : [TUBER] diagnostic
[TUBER] type de tuberculose:tuberculose-maladieIndex. décimale : TU 5. Méthodes de diagnostic En ligne : https://doi.org/10.1183/13993003.00978-2015 Format de la ressource électronique : HTML, PDF Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=9434 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : Lung function predicts lung cancer risk in smokers : a tool for targeting screening programmes Type de document : texte imprimé Auteurs : E. Calabro, Auteur Editeur : European Respiratory Society (ERS) Année de publication : 2010 Collection : European Respiratory Journal num. 35 (1) Importance : p.146-151 Langues : Anglais (eng) Catégories : [TABAC] tabagisme:pathologie:cancer:cancer du poumon
[TABAC] tabagisme:pathologie:cancer:dépistage
[TABAC] tabagisme:risque:facteur associé
[TABAC] tabagisme:tabagisme actif:fumeurIndex. décimale : TA 3.2.2.3 Cancer Résumé : The relationship between smoking, lung cancer and airflow obstruction is recognised but it is unclear whether the presence of minimal lung function damage constitutes an independent risk factor for the development of lung cancer. In order to identify those individuals at higher risk of lung cancer on the basis of functional impairment, we evaluated baseline pulmonary function tests of 3,806 heavy smokers undergoing annual chest computed tomography screening, and compared the forced expiratory volume in 1 s (FEV1) % predicted of 57 lung cancer cases and that of 3,749 subjects without cancer. We obtained odds ratios (ORs) of lung cancer and the corresponding 95% confidence intervals (CIs) using unconditional logistic regression, adjusting for age, sex, study and smoking variables. Compared with subjects with FEV1 ?90% pred, the OR of lung cancer was 2.45 (95% CI 1.39–4.33) for subjects with FEV1 <90% pred and 2.90 (95% CI 1.34–6.27) for subjects with FEV1 <70% pred. These data show that even a relatively small reduction in FEV1 % pred is a significant predictor of increased lung cancer risk. Test screening for lung cancer using airflow obstruction with FEV1 <90% is a strategy worth future consideration. En ligne : https://erj.ersjournals.com/content/35/1/146.long Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=2704 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Management of patients with multidrugresistant/ extensively drug-resistant tuberculosis in Europe / Christoph Lange (2014)
Titre : Management of patients with multidrugresistant/ extensively drug-resistant tuberculosis in Europe : a TBNET consensus statement Type de document : document électronique Auteurs : Christoph Lange, Auteur Editeur : European Respiratory Society (ERS) Année de publication : 2014 Collection : European Respiratory Journal num. 44 Importance : p.23-63 Langues : Français (fre) Catégories : [DIVERS] géographie:Europe
[TUBER] prévention:recommandation
[TUBER] traitement:résistance:multirésistance:extrarésistanceIndex. décimale : TU 3.2. MDR (Multi Drug Resistance) / XDR (X-treme Drug Resistance) En ligne : 10.1183/09031936.00188313 Format de la ressource électronique : HTML, PDF Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=9390 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Maternal smoking during pregnancy induces airway remodelling in mice offspring / M.J. Blacquière (2009)
Titre : Maternal smoking during pregnancy induces airway remodelling in mice offspring Type de document : texte imprimé Auteurs : M.J. Blacquière, Auteur ; W. Timens, Auteur ; B.N. Melgert, Auteur ; M. Geerlings, Auteur Editeur : European Respiratory Society (ERS) Année de publication : 2009 Collection : European Respiratory Journal num. 33 Importance : p. 1133-1140 Présentation : graph., photos, schéma Langues : Anglais (eng) Catégories : [TABAC] tabagisme:tabagisme actif:tabagisme féminin:tabagisme durant la grossesse Index. décimale : TA 3.2.2.7 Grossesse et fœtus Résumé : Children from smoking mothers have an increased risk of developing asthma for reasons largely unknown. The effects of maternal smoking during pregnancy on remodelling, allergic airway inflammation and hyperresponsiveness in offspring were investigated in an experimental asthma model. Mice were exposed to fresh air or cigarette smoke from 3 weeks prior to conception until birth. Offspring were exposed to house dust mite (HDM) or PBS intranasally four times per week from week 5 to week 10 after birth onwards. Maternal smoking increased airway smooth muscle layer, collagen III deposition and HDM-induced goblet cell numbers in offspring. It additionally increased methacholine responsiveness, which correlated significantly with increased airway smooth muscle layer and collagen deposition. Maternal smoking increased HDM-induced numbers of neutrophils and mast cells in lung tissue. No further effects were observed. Smoking during pregnancy induces airway remodelling in mice offspring, which may contribute to increased methacholine responsiveness. This takes place irrespective of allergen exposure but may worsen the outcome of the allergic stimulus, resulting in higher methacholine responsiveness in house dust mite-exposed offspring from smoking mothers when compared to nonsmoking mothers. The results provide a possible mechanism behind the association between maternal smoking and asthma. En ligne : https://erj.ersjournals.com/content/33/5/1133.long Format de la ressource électronique : HTML Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=8055 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Mechanisms of clearance of nontypeable Haemophilus influenzae from cigarette smoke-exposed mouse lung / G.J. Gaschler (2010)
Titre : Mechanisms of clearance of nontypeable Haemophilus influenzae from cigarette smoke-exposed mouse lung Type de document : texte imprimé Auteurs : G.J. Gaschler, Auteur ; C.C.J. Zavitz, Auteur ; C.M.T. Bauer, Auteur ; M.R. Stämpfli, Auteur Editeur : European Respiratory Society (ERS) Année de publication : 2010 Collection : European Respiratory Journal num. 36 Importance : p. 1131-1142 Présentation : graph. Langues : Anglais (eng) Catégories : [TABAC] chimie du tabac:fumée
[TABAC] tabagisme:pathologie:pathologie respiratoire:broncho-pneumopathie chronique obstructiveIndex. décimale : TA 3.2.2.1 Expérimentation Résumé : Inflammation is prevalent in all stages of chronic obstructive pulmonary disease, and, furthermore, individuals undergo periods of exacerbation, during which pulmonary inflammation increases, often a result of bacterial infection. The present study investigates the in vivo consequences of cigarette smoke exposure on bacterial challenge with nontypeable Haemophilus influenzae (NTHi). BALB/c and C57 black 6 (C57BL/6) mice were exposed to cigarette smoke once or twice daily for a total period of 8 weeks. Exacerbated inflammation was observed in cigarette smoke-exposed compared to room-air-exposed mice following challenge with live or heat-inactivated NTHi. Accelerated clearance of live NTHi from cigarette smoke-exposed mice was independent of the establishment of chronic inflammation or direct toxic effects of cigarette smoke components on bacteria. Mechanistically, a cell-free factor in the bronchoalveolar lavage fluid contributed to accelerated clearance following passive transfer to naive mice. Further investigation demonstrated increased titres of immunoglobulin A in the bronchoalveolar lavage fluid, but not the blood, of cigarette smoke-exposed mice, including increased titres of NTHi-specific immunoglobulin A, whereas heavy chain joining element (J(H))(-/-) B-cell-deficient cigarette smoke-exposed mice did not demonstrate decreased bacterial burden following challenge. The present results demonstrate that cigarette smoke exposure results in exacerbated inflammation following challenge with NTHi, as well as increased titres of antibodies that contribute to bacterial clearance. En ligne : https://erj.ersjournals.com/content/36/5/1131 Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=8074 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité TA 005625 TA 3.2.2.1 GAS M Article/Périodique Bibliothèque FARES Tabac Consultation sur place
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