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Titre : Active smoking compromises IVF outcome and affects ovarian reserve Type de document : document électronique Auteurs : Thomas Freour, Auteur ; Damien Masson, Auteur ; Sophie Mirallie, Auteur ; Kalyane Bach, Auteur ; Miguel Jean, Auteur ; Thomas Dejoie, Auteur ; Paul Barriere, Auteur Editeur : Elsevier Science Direct Année de publication : 2008 Collection : Reproductive BioMedicine Online, ISSN 1472-6491 num. vol.16 n°1 Importance : p.96-102 Langues : Français (fre) Catégories : [TABAC] tabagisme:effet du tabac:altération de la fonction sexuelle:effet sur la fertilité
[TABAC] tabagisme:risque:facteur associé:grossesseIndex. décimale : TA 3.2.2.7 Grossesse et fœtus Résumé : Although the association between smoking and female infertility is now largely demonstrated, the proportion of smokers in women of reproductive age remains important. Tobacco contains numerous toxicants that could affect ovarian reserve and lead to poor prognosis in assisted reproductive techniques. To investigate the effect of female active smoking on ovarian reserve and IVF outcome, smoking status, hormonal status, i.e. serum FSH, oestradiol and anti-Müllerian hormone (AMH), ovarian response to hyperstimulation, i.e. mature oocytes retrieved, and IVF outcome, i.e. clinical pregnancy, were retrospectively analysed in 111 women undergoing IVF-embryo transfer cycles. Compared with non-smokers (n = 71), active smoking women (n = 40) had decreased ovarian response (12.12 ± 5 versus 8.62 ± 4 mature oocytes retrieved) to hyperstimulation and lower clinical pregnancy rate (29.6 versus 10.0%). Serum AMH concentrations were lower in the smoker group (3.86 ± 1.92 versus 3.06 ± 1.68 μg/l) and had no predictive value for ovarian response, inversely to non-smokers. In conclusion, active smoking is associated with poor prognosis in assisted reproduction cycles, i.e. ovarian response and pregnancy, and leads to altered ovarian reserve, as reflected by decreased serum AMH concentrations. En ligne : https://doi.org/10.1016/S1472-6483(10)60561-5 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10104 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : An in vitro toxicological assessment of two electronic cigarettes : e-liquid to aerosolisation Type de document : document électronique Auteurs : E. Bishop, Auteur ; F. Miazzi, Auteur ; S. Bozhilova, Auteur Editeur : Elsevier Science Direct Année de publication : 2024 Collection : Current Research in Toxicology num. 6 Importance : 36 p. Présentation : ill., tab., graph. Langues : Anglais (eng) Catégories : [TABAC] CANDIDATS:e-cigarette
[TABAC] chimie du tabac:constituant:additif:agent de saveur
[TABAC] chimie du tabac:tabac fumé:cigarette:cigarette électronique
[TABAC] étude
[TABAC] tabagisme:tabagisme passifMots-clés : arôme - e-liquide - mécanisme de l'appareil- vapotage hors tabagisme passif - toxicologie - aérosol - test dans le sens de tester les produits, l'appareil Index. décimale : TA 1.1.1 Cigarettes (« normales », électroniques, aromatisées,…) Résumé : Interest in the toxicological assessment of iterations of e-cigarette devices, e-liquid formulations and flavour use is increasing. Here, we describe a multiple test matrix and
in vitro approach to assess the biological impact of differing e-cigarette activation mechanism (button vs puff-activated) and heating technology (cotton vs ceramic wick). The e-liquids selected for each device contained the same nicotine concentration and flavourings. We tested both e-liquid and aqueous extract of e-liquid aerosol using a high throughput
cytotoxicity and genotoxicity screen. We also conducted whole aerosol assessment both in a reconstituted human airway lung tissue (MucilAir) with associated endpoint assessment
(cytotoxicity, TEER, cilia beat frequency and active area) and an Ames whole aerosol assay with up to 900 consecutive undiluted puffs. Following this testing it is shown that the
biological impact of these devices is similar, taking into consideration the limitations and capturing efficiencies of the different testing matrices. We have contextualised these
responses against previous published reference cigarette data to establish the comparative reduction in response consistent with reduced risk potential of the e-cigarette products
tested in this study as compared to conventional cigarettes.Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10187 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Classification of patterns of tobacco and cannabis co-use based on temporal proximity / Nhung Nguyen (2024)
Titre : Classification of patterns of tobacco and cannabis co-use based on temporal proximity : a qualitative study among young adults Type de document : document électronique Auteurs : Nhung Nguyen, Auteur ; Sabrina Islam, Auteur ; Karla D. Llanes, Auteur ; Kimberly A. Koester, Auteur ; Pamela M. Ling, Auteur Editeur : Elsevier Science Direct Année de publication : 2024 Collection : Addictive Behaviors num. 152 Importance : 8 p. Présentation : ill., tab. Langues : Anglais (eng) Catégories : [DIVERS] personne:par âge:jeune
[TABAC] étude
[TABAC] tabagisme:risque:facteur associé:drogue:cannabisIndex. décimale : TA 1.1.5 Cannabis Résumé : Purpose:
Co-use of tobacco and cannabis is a common and complex behavior. The lack of harmonized measures of co-use yields confusion and inconsistencies in synthesizing evidence about the health effects of co-use. We aimed to classify co-use patterns based on temporal proximity and describe preferred products and motives for each
pattern in order to improve co-use surveillance.
Methods: We conducted semi-structured interviews in a sample of 34 young adults (Mage = 22.8 years, 32.4 % female) during 2017–2019 in California, USA. We employed a qualitative thematic analysis to identify timing, reasons, and contexts for tobacco and cannabis co-use and classify co-use patterns.
Results:
Four emergent patterns of co-use with increasing temporal proximity between tobacco use and cannabis use were: Same-month different-day co-use (Pattern 1); Same-day different-occasion co-use (Pattern 2); Same-occasion sequential co-use (Pattern 3); and Same-occasion simultaneous co-use (Pattern 4). Participants used various product combinations within each pattern. Similar motives for all patterns were socialization, product availability, and coping with stress/anxiety. Unique motive for temporally distant patterns (Patterns 1 and 2) was seeking substancespecific effects (e.g., stimulant effect from nicotine, relaxation effects from cannabis), while unique motives for temporally close patterns (Patterns 3 and 4) were seeking combined effects from both substances (e.g., more intense psychoactive effects, mitigating cannabis adverse effects) and behavioral trigger (e.g., cannabis use triggers tobacco use).
Conclusions:
Our classification of co-use patterns can facilitate consistency for measuring co-use and assessing its health impacts. Future research should also measure product types and motives for different patterns to inform intervention efforts.Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10207 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : Comparison of cellulose vs. plastic cigarette filter decomposition under distinct disposal environments Type de document : document électronique Auteurs : François-Xavier Joly, Auteur ; Mathieu Coulis, Auteur Editeur : Elsevier Science Direct Année de publication : 2017 Collection : Waste Management, ISSN 1879-2456 num. 72 Importance : p.349-353 Présentation : tab., graph. Langues : Anglais (eng) Catégories : [TABAC] chimie du tabac:tabac fumé:cigarette:cigarette filtre
[TABAC] tabagisme:effet sur l'environnement:mégot
[TABAC] tabagisme:effet sur l'environnement:pollutionIndex. décimale : TA 1.1.1 Cigarettes (« normales », électroniques, aromatisées,…) Résumé : It is estimated that 4.5 trillion cigarette butts are discarded annually, making them numerically the most common type of litter on Earth. To accelerate their disappearance after disposal, a new type of cigarette filters made of cellulose, a readily biodegradable compound, has been introduced in the market. Yet, the
advantage of these cellulose filters over the conventional plastic ones (cellulose acetate) for decomposition, remains unknown. Here, we compared the decomposition of cellulose and plastic cigarettes filters, either intact or smoked, on the soil surface or within a composting bin over a six-month field decomposition experiment. Within the compost, cellulose filters decomposed faster than plastic filters, but this advantage was strongly reduced when filters had been used for smoking. This indicates that the accumulation of tars and other chemicals during filter use can strongly affect its subsequent decomposition.
Strikingly, on the soil surface, we observed no difference in mass loss between cellulose and plastic filters throughout the incubation. Using a first order kinetic model for mass loss of for used filters over the short period of our experiment, we estimated that conventional plastic filters take 7.5–14 years to disappear, in the compost and on the soil surface, respectively. In contrast, we estimated that cellulose filters take 2.3– 13 years to disappear, in the compost and on the soil surface, respectively. Our data clearly showed that disposal environments and the use of cellulose filters must be considered when assessing their advantage over plastic filters. In light of our results, we advocate that the shift to cellulose filters should not exempt users from disposing their waste in appropriate collection systems.
En ligne : https://doi.org/10.1016/j.wasman.2017.11.023 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=9804 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : Genotoxicity of environmental tobacco smoke : a review Type de document : document électronique Auteurs : Kristi Husgafvel-Pursiainen, Auteur Editeur : Elsevier Science Direct Année de publication : 2004 Collection : Mutation Research: Reviews in Mutation Research, ISSN 1388-2139 num. 567 Importance : p.427–445 Langues : Anglais (eng) Catégories : [TABAC] tabagisme:risque:facteur associé:génétique
[TABAC] tabagisme:tabagisme passifIndex. décimale : TA 7.4 Effets du tabagisme passif Résumé : Environmental tobacco smoke (ETS), or second-hand smoke, is a widespread contaminant of indoor air in environments where smoking is not prohibited. It is a significant source of exposure to a large number of substances known to be hazardous to human health. Numerous expert panels have concluded that there is sufficient evidence to classify involuntary smoking (or passive smoking) as carcinogenic to humans. According to the recent evaluation by the International Agency for Research on Cancer, involuntary smoking causes lung cancer in never-smokers with an excess risk in the order of 20% for women and 30% for men. The present paper reviews studies on genotoxicity and related endpoints carried out on ETS since the mid-1980s. The evidence from in vitro studies demonstrates induction of DNA strand breaks, formation of DNA adducts, mutagenicity in bacterial assays and cytogenetic effects. In vivo experiments in rodents have shown that exposure to tobacco smoke, whole-body exposure to mainstream smoke (MS), sidestream smoke (SS), or their mixture, causes DNA single strand breaks, aromatic adducts and oxidative damage to DNA, chromosome aberrations and micronuclei. Genotoxicity of transplacental exposure to ETS has also been reported. Review of human biomarker studies conducted among non-smokers with involuntary exposure to tobacco smoke indicates presence of DNA adducts, urinary metabolites of carcinogens, urinary mutagenicity, SCEs and hypoxanthine-guanine phosphoribosyltransferase (HPRT) gene mutations (in newborns exposed through involuntary smoking of the mother). Studies on human lung cancer from smokers and never-smokers involuntarily exposed to tobacco smoke suggest occurrence of similar kinds of genetic alterations in both groups. In conclusion, these overwhelming data are compatible with the current knowledge on the mechanisms of carcinogenesis of tobacco-related cancers, occurring not only in smokers but with a high biological plausibility also in involuntary smokers.
En ligne : https://doi.org/10.1016/j.mrrev.2004.06.004 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10025 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : High-quality embryos maintain high pregnancy rates in passive smokers but not in active smokers Type de document : document électronique Auteurs : Avi Ben-Haroush, Auteur ; Jacob Ashkenazi, Auteur ; Onit Sapir, Auteur ; Haim Pinkas, Auteur ; Benjamin Fisch, Auteur ; Jacob Farhi, Auteur Editeur : Elsevier Science Direct Année de publication : 2011 Collection : Reproductive BioMedicine Online, ISSN 1472-6491 num. 22(1) Importance : p.44-49 Langues : Anglais (eng) Catégories : [TABAC] étude
[TABAC] tabagisme:effet du tabac:altération de la fonction sexuelle:effet sur la fertilité
[TABAC] tabagisme:risque:facteur associé:grossesse
[TABAC] tabagisme:tabagisme actif
[TABAC] tabagisme:tabagisme passifIndex. décimale : TA 3.2.2.7 Grossesse et fœtus Résumé : This study assesses the effect of passive and active smoking on pregnancy rates after IVF with transfer of high-quality embryos. In a cohort study, women attending the IVF unit in 2006–2007 with favourable parameters for pregnancy (<38 years; less than three IVF cycles, transfer of two highest-grade embryos) grouped by smoking status were included. The cohort included 237 patients/cycles: 42 smokers, 195 non-smokers. The clinical pregnancy rate was significantly lower in smokers (35.7% versus 55.4%,P = 0.021, OR = 0.44 (95% CI 0.22–0.89)), even after conditional stratification on covariates (passive smoker, passive or partner smoker, age group). The live-birth rate was lower in smokers (28.6% versus 42.6%), but the difference was not statistically significant(OR = 0.54 (0.26–1.11)). Among non-smokers, there was no difference in pregnancy rate by passive or partner smoking. On logistic regression, variables predicting pregnancy were age <35 years (P = 0.008, OR = 2.58 (1.2–5.2)) and non-smoking (P = 0.003,OR = 3.47 (1.51–7.98)). In conclusion, transfer of high-quality embryos does not overcome the negative effect of active smoking on pregnancy rate in IVF treatment. The endometrium is apparently involved in the mechanism underlying IVF failure in smokers. En ligne : https://doi.org/10.1016/j.rbmo.2010.09.012 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10101 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : Quantification of benzo[a]pyrene and other PAHs in the serum and follicular fluid of smokers versus non-smokers Type de document : document électronique Auteurs : Michael S. Neal, Auteur ; Jiping Zhu, Auteur ; Warren G. Foster, Auteur Editeur : Elsevier Science Direct Année de publication : 2008 Collection : Reproductive Toxicology num. 25 Importance : p.100-106 Langues : Anglais (eng) Catégories : [TABAC] tabagisme:effet du tabac:altération de la fonction sexuelle:effet sur la fertilité
[TABAC] tabagisme:tabagisme actif:fumeur
[TABAC] tabagisme:tabagisme passif:non-fumeurIndex. décimale : TA 3.2.2.7 Grossesse et fœtus Résumé : Cigarette smoking is a well-established reproductive hazard that has been linked with decreased fertility in both smokers and those exposed to
second hand smoke. The chemical components responsible for the reproductive toxic effects of cigarette smoke are unknown. Moreover, exposure
of reproductive tissues to the chemical constituents of cigarette smoke is largely unknown. Therefore, we measured the levels of benzo[a]pyrene
(B[a]P), and other polycyclic aromatic hydrocarbons (PAH) present in cigarette smoke, in the serum and follicular fluid of women exposed to
mainstream (n = 19) and side stream smoke (n = 7) compared to non-smokers (n = 10). Women exposed to mainstream smoke had significantly
higher levels of B[a]P (1.32 ± 0.68 ng/ml) in their follicular fluid compared to side stream exposed (0.05 ± 0.01 ng/ml) or their non-smoking
(0.03 ± 0.01 ng/ml) counterparts. More importantly we found significantly higher (p < 0.001) levels of B[a]P in the follicular fluid of women
who did not conceive (1.79 ± 0.03 ng/ml) compared to those that achieved a pregnancy (0.08 ± 0.03 ng/ml). Other PAHs known to be present in
cigarette smoke were also detectable in both serum and follicular fluid of study subjects studied but with lower frequency compared to B[a]P and
no differences in serum or follicular fluid levels between the groups could be demonstrated. The important finding that B[a]P reaches the follicular
fluid and the fact that it is found at much higher levels in women who smoke provides further evidence that of the many toxicants present in
cigarette smoke, B[a]P may be a key compound that is central to the documented adverse effects of cigarette smoke on follicular development and
subsequent fertility.En ligne : https://doi.org/10.1016/j.reprotox.2007.10.012 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10106 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Rationale, pharmacology and clinical efficacy of partial agonists of alpha4beta2 nACh receptors for smoking cessation / Hans Rollema (2007)
Titre : Rationale, pharmacology and clinical efficacy of partial agonists of alpha4beta2 nACh receptors for smoking cessation Type de document : texte imprimé Auteurs : Hans Rollema, Auteur ; Jotham W. Coe, Auteur ; L. K. Chambers, Auteur ; Raymond S. Hurst, Auteur Editeur : Elsevier Science Direct Année de publication : 2007 Collection : Trends in pharmacological sciences num. 28:7 Importance : p. 316-325 Présentation : ill., graph., tab. Langues : Anglais (eng) Catégories : [TABAC] chimie du tabac:constituant:alcaloïde:nicotine:récepteur nicotinique Index. décimale : TA 6.2.3 Approche pharmacologique Résumé : Most smokers repeatedly fail in their attempts to stop smoking because of the addictive nature of the nicotine in tobacco products. Nicotine dependence is probably mediated through the activation of multiple subtypes of neuronal nicotinic acetylcholine receptor (nAChR), among which the mesolimbic alpha(4)beta(2) subtype has a pivotal role. Here, we discuss the rationale for and the design of alpha(4)beta(2) nAChR partial agonists as novel treatments for tobacco addiction. Such agents are expected to exhibit a dual action by sufficiently stimulating alpha(4)beta(2)-nAChR-mediated dopamine release to reduce craving when quitting and by inhibiting nicotine reinforcement when smoking. Potent and selective alpha(4)beta(2) nAChR partial agonists that exhibit dual agonist and antagonist activity in preclinical models can be identified. The validity of this approach is demonstrated by the clinical efficacy of the alpha(4)beta(2) nAChR partial agonist varenicline, which has significantly better quit rates than do other treatments and offers a new option for smoking cessation pharmacotherapy. En ligne : https://doi.org/10.1016/j.tips.2007.05.003 Format de la ressource électronique : PDF, HTML Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=8367 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité TA 005998 TA 6.2.3 ROL R Article/Périodique Bibliothèque FARES Tabac Consultation sur place
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Titre : Varenicline has antidepressant-like in activity in the forced swim test augments sertraline's effect Type de document : texte imprimé Auteurs : Hans Rollema, Auteur ; Victor Guanowsky, Auteur ; Yann S. Mineur, Auteur Editeur : Elsevier Science Direct Année de publication : 2009 Collection : European Journal of Pharmacology, ISSN 0014-2999 num. Vol 605 Importance : p. 114-116 Présentation : graph. Langues : Anglais (eng) Catégories : [TABAC] étude
[TABAC] sevrage tabagique:méthode de sevrage:méthode individuelle:approche pharmacologique:varéniclineIndex. décimale : TA 6.2.3.1.4 Autres substituts nicotiniques Résumé : Varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist developed as a smoking cessation aid, showed antidepressant-like activity in the forced swim test in two mouse strains. In addition, a low varenicline dose significantly enhanced the effects of moderately active doses of the selective serotonin reuptake inhibitor sertraline. These findings are consistent with the notion that reducing alpha4beta2 nicotinic acetylcholine receptor activity either by antagonists or by partial agonists that can partially activate or desensitize acetylcholine receptors is associated with antidepressant-like properties. These data suggest that varenicline may have antidepressant potential and can, when combined, augment antidepressant responses of selective serotonin reuptake inhibitors. Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=7946 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité TA 005487 TA 6.2.3.1.4 ROL V Article/Périodique Bibliothèque FARES Tabac Consultation sur place
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