| Titre : |
High-quality embryos maintain high pregnancy rates in passive smokers but not in active smokers |
| Type de document : |
document électronique |
| Auteurs : |
Avi Ben-Haroush, Auteur ; Jacob Ashkenazi, Auteur ; Onit Sapir, Auteur ; Haim Pinkas, Auteur ; Benjamin Fisch, Auteur ; Jacob Farhi, Auteur |
| Editeur : |
Elsevier Science Direct |
| Année de publication : |
2011 |
| Collection : |
Reproductive BioMedicine Online, ISSN 1472-6491 num. 22(1) |
| Importance : |
p.44-49 |
| Langues : |
Anglais (eng) |
| Catégories : |
[TABAC] étude
[TABAC] tabagisme:effet du tabac:altération de la fonction sexuelle:effet sur la fertilité
[TABAC] tabagisme:risque:facteur associé:grossesse
[TABAC] tabagisme:tabagisme actif
[TABAC] tabagisme:tabagisme passif
|
| Index. décimale : |
TA 3.2.2.7 Grossesse et fœtus |
| Résumé : |
This study assesses the effect of passive and active smoking on pregnancy rates after IVF with transfer of high-quality embryos. In a cohort study, women attending the IVF unit in 2006–2007 with favourable parameters for pregnancy (<38 years; less than three IVF cycles, transfer of two highest-grade embryos) grouped by smoking status were included. The cohort included 237 patients/cycles: 42 smokers, 195 non-smokers. The clinical pregnancy rate was significantly lower in smokers (35.7% versus 55.4%,P = 0.021, OR = 0.44 (95% CI 0.22–0.89)), even after conditional stratification on covariates (passive smoker, passive or partner smoker, age group). The live-birth rate was lower in smokers (28.6% versus 42.6%), but the difference was not statistically significant(OR = 0.54 (0.26–1.11)). Among non-smokers, there was no difference in pregnancy rate by passive or partner smoking. On logistic regression, variables predicting pregnancy were age <35 years (P = 0.008, OR = 2.58 (1.2–5.2)) and non-smoking (P = 0.003,OR = 3.47 (1.51–7.98)). In conclusion, transfer of high-quality embryos does not overcome the negative effect of active smoking on pregnancy rate in IVF treatment. The endometrium is apparently involved in the mechanism underlying IVF failure in smokers. |
| En ligne : |
https://doi.org/10.1016/j.rbmo.2010.09.012 |
| Format de la ressource électronique : |
Article en ligne |
| Permalink : |
https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10101 |
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High-quality embryos maintain high pregnancy rates in passive smokers but not in active smokers (2011)
