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Titre : An overview of e-cigarette impact on reproductive health Type de document : document électronique Auteurs : Debbie Montjean, Auteur ; Marie-Hélène Godin Pagé, Auteur ; Marie-Claire Bélanger, Auteur Editeur : Bâle [Suisse] : MDPI AG (Molecular Diversity Preservation International) Année de publication : 2023-03-18 Importance : 14 p. Présentation : tab., ill. Langues : Anglais (eng) Catégories : [DIVERS] personne:par sexe:femme
[DIVERS] personne:par sexe:homme
[TABAC] chimie du tabac:constituant:alcaloïde:nicotine
[TABAC] chimie du tabac:tabac fumé:cigarette:cigarette électronique
[TABAC] tabagisme:effet du tabac:altération de la fonction sexuelle
[TABAC] tabagisme:effet du tabac:altération de la fonction sexuelle:effet sur la fertilité
[TABAC] tabagisme:risque:facteur associé:grossesse:procréation médicalement assistéeMots-clés : :"procréation médicalement" assistée à défaut d'autre chose
système reproducteurIndex. décimale : TA 1.1.1 Cigarettes (« normales », électroniques, aromatisées,…) Résumé : Abstract:
Electronic cigarettes (e-cigarettes) are often considered a “safe substitute” for conventional cigarette cessation. The composition of the fluid is not always clearly defined and shows a large variation within brands and manufacturers. More than 80 compounds were detected in liquids and aerosols. E-cigarettes contain nicotine, and the addition of flavorings increases the toxicity of e-cigarette vapour in a significant manner. The heat generated by the e-cigarette leads to the oxidation
and decomposition of its components, eventually forming harmful constituents in the inhaled vapour. The effects of these toxicants on male and female reproduction are well established in conventional cigarette smokers. Although toxins were measured at much lower levels in e-cigarette aerosols compared to smoke from a conventional cigarette, there are concerns about their potential impact on male and female reproduction. The information available was mainly obtained from studies conducted in animal models, and investigations in humans are scarce. However, the effects observed in animal models suggest that caution should be taken when vaping and that more research needs to be conducted to identify its potential adverse effects on fertility. The prevalence of e-cigarette usage is alarming, and warnings should be made about the impact of vaping on reproductive health. This document reviews the data regarding the impact of e-cigarette use on male and female reproductionPermalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=9828 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : Effectiveness of the electronic cigarette : an eight-week Flemish study with six-month follow-up on smoking reduction, craving and experienced benefits and complaints Type de document : texte imprimé Auteurs : Karolien Adriaens, Auteur ; Dinska Van Gucht, Auteur ; Paul Declerck, Auteur Editeur : Bâle [Suisse] : MDPI AG (Molecular Diversity Preservation International) Année de publication : novembre 2014 Collection : International Journal of Environmental Research and Public Health, ISSN 1660-4601 num. 11:11 Importance : p.11220-11248 Langues : Anglais (eng) Catégories : [DIVERS] géographie:Europe:Europe occidentale:Belgique
[TABAC] chimie du tabac:tabac fumé:cigarette:cigarette électronique
[TABAC] étude
[TABAC] sevrage tabagique
[TABAC] tabagisme:aspect psychologique:comportement:addictionIndex. décimale : TA 1.1.1 Cigarettes (« normales », électroniques, aromatisées,…) Résumé : Les cigarettes électroniques offrent aux fumeurs un moyen réaliste d’abandonner leur dépendance au tabac. Dans une nouvelle étude publiée dans la Revue internationale de la recherche environnementale et de la santé publique , des scientifiques de la KU Leuven ont déclaré que les cigarettes électroniques réduisaient avec succès l'envie de fumer des cigarettes de tabac, avec seulement des effets secondaires minimes. En ligne : https://doi.org/10.3390/ijerph111111220 Format de la ressource électronique : PDF, HTML Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=8946 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité TA 006972 TA 6.2.3.2 ECI Article/Périodique Bibliothèque FARES Tabac Consultation sur place
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Titre : Effects of vape use on oral health : a review of the literature Type de document : document électronique Auteurs : Alin M. Iacob, Auteur ; Matías F. Escobedo Martínez, Auteur ; Enrique Barbeito Castro, Auteur Editeur : Bâle [Suisse] : MDPI AG (Molecular Diversity Preservation International) Année de publication : 2024 Collection : Medicina Importance : 11 p. Présentation : tab. Langues : Anglais (eng) Catégories : [TABAC] CANDIDATS:e-cigarette
[TABAC] tabagisme:effet du tabac:effet bucco-dentaireMots-clés : revue de la littérature Index. décimale : TA 1.1.1 Cigarettes (« normales », électroniques, aromatisées,…) Résumé : Background and Objectives:
The widespread use of tobacco has evolved with the popularity of vapes, especially among young people, despite the lack of clarity in warnings about their risks.
Studies indicate the need for more effective communication about the oral risks of vaping. In addition to systemic, respiratory, and cardiovascular effects, vaping is associated with an increased risk of gingivitis and periodontal disease as well as reduced antioxidant capacity of saliva. The objectives of this narrative review are to summarize the existing information in the literature on the effects of
vaping at the oral level and to bring together knowledge about the mechanism of action of vaping in
oral tissues.
Materials and Methods:
In the present study, articles were searched in PubMed, Elsevier Scopus, and Web of Science using the keywords “oral health”, “vaping”, and “vape”. Studies published
in the last 6 years that addressed the effects of oral vaping were selected, including comparisons among vape users, smokers, and non-smokers. Repeated articles, prior to 2017 and in languages other than English, were excluded. Two review authors (A.M.I and M.F.E.M) independently selected the papers based on titles and abstracts and conducted a full review of the remaining papers. In cases of disagreement, a third reviewer was used.
Results:
A total of 113 results were obtained, distributed as 16 from PubMed, 35 fromWeb of Science, and 62 from Elsevier Scopus. After removing duplicates, 67 articles were filtered by reviewing titles and abstracts, and finally, 22 articles were selected for comprehensive reading. Subsequently, eight of these articles were chosen for qualitative synthesis and are presented in standardized tables. The sample size of all included studies was composed of 31,647 participants, (14,477 male and 17,170 female) with a mean of 35.016 ± 7.57 years of age.
Conclusions: This review indicates that the use of vapes is associated with an increased risk of periodontitis and caries. Although users experience more oral problems than non-smokers, these are less severe than those of traditional smokers. The widespread prevalence, especially among young people, highlights the urgency of awareness campaigns to warn of risks and understand potential harm.En ligne : https://doi.org/10.3390/medicina60030365 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10304 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Evaluation of cytotoxic and genotoxic effects in buccal mucosal cells in non-smokers and users of traditional combustible tobacco products and non-combustible alternatives / Antonija Tadin (2024)
Titre : Evaluation of cytotoxic and genotoxic effects in buccal mucosal cells in non-smokers and users of traditional combustible tobacco products and non-combustible alternatives Type de document : document électronique Auteurs : Antonija Tadin, Auteur ; Vinka Stazic, Auteur ; Nada Galic, Auteur ; Davor Zeljezic, Auteur Editeur : Bâle [Suisse] : MDPI AG (Molecular Diversity Preservation International) Année de publication : 2024 Collection : Journal of xenobiotics num. 14 Importance : p. 155-165 Présentation : graph., tab. Langues : Anglais (eng) Catégories : [TABAC] CANDIDATS:e-cigarette
[TABAC] étude
[TABAC] tabagisme:effet du tabac:effet bucco-dentaire
[TABAC] tabagisme:effet du tabac:toxicitéIndex. décimale : TA 1.1.1 Cigarettes (« normales », électroniques, aromatisées,…) Résumé : Aims/Objectives: The aim of this cross-sectional observational study was to investigate cytogenetic damage to the buccal mucosa in non-smokers and consumers of traditional combustible tobacco products and non-combustible alternatives.
Methods: A total of 160 participants were divided into four groups according to the type of product used, including non-smokers, users of conventional combustible tobacco (cigarettes), heated tobacco, and electronic, tobacco-free vapor products (e-cigarettes). Buccal mucosa samples were analyzed using the micronucleus cytome assay
to assess cytotoxic and genotoxic damage.
Results: E-cigarette users showed significantly higher values for all tested parameters in the micronucleus test compared to non-smokers (p < 0.05). Similarly, users of tobacco heating products showed an increase in all parameters (p < 0.05), with the exception of the number of cells with micronuclei. Conventional cigarette smokers showed a notable increase in the number of binucleated cells and cells with karyorrhexis and karyolysis (p ≤ 0.05). When assessing the differences between users of traditional combustible tobacco products and non-combustible alternatives, these did not appear to be significant, except for e-cigarette users, who had significantly more cells with condensed chromatin (p ≤ 0.001), while users of tobacco heating products had more pyknotic cells (p ≤ 0.001).
Conclusion: The results of this study underscore the heightened occurrence of cytotoxic and genotoxic damage in users of both conventional combustible tobacco products and non-combustible alternatives compared to non-smokers, emphasizing the detrimental impact of these products on the oral mucosa.
Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10179 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : Exposure to e-cigarette advertisements or reviews and e-cigarette use progression : a longitudinal examination of short-term and long-term associations among US young adults Type de document : document électronique Auteurs : Zongshuan Duan, Auteur ; Katelyn F. Romm, Auteur ; Yan Wang, Auteur Editeur : Bâle [Suisse] : MDPI AG (Molecular Diversity Preservation International) Année de publication : 2024 Collection : International Journal of Environmental Research and Public Health, ISSN 1660-4601 Importance : 13 p. Présentation : tab. Langues : Anglais (eng) Catégories : [DIVERS] géographie:Amérique:Amérique du Nord:Etats-Unis
[DIVERS] personne:par âge:adulte
[DIVERS] personne:par âge:jeune
[TABAC] CANDIDATS:e-cigarette
[TABAC] économie du tabac:marketing:publicité:publicité pro-tabac:publicité directe
[TABAC] étudeIndex. décimale : TA 1.1.1 Cigarettes (« normales », électroniques, aromatisées,…) Résumé : Limited research has investigated the impact of e-cigarette advertising and reviews on the progression of e-cigarette use among young adults in the US. This study utilized five-wave longitudinal data (2018–2020) with 3006 young adults aged 18–34, reporting exposure to e-cigarette advertisements or reviews atWave 1 (W1) and W3. Generalized estimating equations (GEE) were used to examine the prospective associations between frequent exposure to e-cigarette advertisements or reviews and e-cigarette use progression in four groups: never users (n = 1271 at W1), former users (previously used but quit ≥ 6 months ago, n = 422 at W1), recent former users (used in the past 6 months but not in the past month, n = 186 at W1), and current users (used in the past month, n = 1127 at W1). Among baseline former users, frequent exposure to e-cigarette reviews was associated with current use at 6-month follow-up (aOR = 4.40, 95%CI = 1.46–13.29). Among
baseline current users, frequent exposure to e-cigarette reviews was associated with increased days of use at 6-month follow-up (IRR = 1.20, 95%CI = 1.07–1.34) and 12-month follow-up (IRR = 1.18, 95%CI = 1.03–1.35). E-cigarette reviews may contribute to relapse among recent former users and increased usage frequency among current users, highlighting the need for enhanced e-cigarette promotional activity regulation.En ligne : https://doi.org/10.3390/ijerph21020123 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10310 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Global reach of an internet smoking cessation intervention among Spanish- and English- speaking from 157 countries / Alinne Z. Barrera (2009)
Titre : Global reach of an internet smoking cessation intervention among Spanish- and English- speaking from 157 countries Type de document : texte imprimé Auteurs : Alinne Z. Barrera, Auteur ; Eliseo J. Pérez-Stable, Auteur ; Kevin L. Delucchi, Auteur ; Ricardo F. Munoz, Auteur Editeur : Bâle [Suisse] : MDPI AG (Molecular Diversity Preservation International) Année de publication : 2009 Collection : International Journal of Environmental Research and Public Health, ISSN 1660-4601 num. 6 Importance : p. 927-940 Présentation : tab. Langues : Anglais (eng) Catégories : [TABAC] étude:enquête
[TABAC] prévention:campagne:campagne médiatique:internet
[TABAC] sevrage tabagique:aide au sevrage:conseil de sevrage
[TABAC] tabagisme:habitude tabagiqueIndex. décimale : TA 6.2 Méthodes individuelles Résumé : This investigation is a secondary analysis of demographic, smoking, and depression information in a global sample of Spanish- and English-speaking smokers who participated in a series of randomized controlled smoking cessation trials conducted via the Internet. The final sample consisted of 17,579 smokers from 157 countries. Smoking profiles were similar across languages and world regions and consistent with characteristics of participants in traditional smoking cessation studies. Participants were predominantly Spanish-speakers, evenly divided between men and women and relatively few indicated using traditional smoking cessation methods (e.g., groups or medication). This study demonstrates that substantial numbers of smokers from numerous countries seek Web-based smoking cessation resources and adds to the growing support for Web-assisted tobacco interventions as an additional tool to address the need for global smoking cessation efforts. En ligne : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672395/ Format de la ressource électronique : HTML, PDF Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=8053 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité TA 005603 TA 6.2 BAR G Article/Périodique Bibliothèque FARES Tabac Consultation sur place
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Titre : Hookah (shisha, narghile) smoking and environmental tobacco smoke (ETS) : a critical review of the relevant literature and the public health consequences Type de document : texte imprimé Auteurs : Kamal Chaouachi, Auteur Editeur : Bâle [Suisse] : MDPI AG (Molecular Diversity Preservation International) Année de publication : 2009 Collection : International Journal of Environmental Research and Public Health, ISSN 1660-4601 num. 6(2) Importance : p.798–843 Langues : Français (fre) Catégories : [TABAC] chimie du tabac:fumée
[TABAC] chimie du tabac:tabac fumé:chicha
[TABAC] prévention:santé:santé publique
[TABAC] tabagisme:tabagisme passif:tabagisme environnementalIndex. décimale : TA 1.1.4 Chicha – Narguilé Résumé : Hookah (narghile, shisha, “water-pipe”) smoking is now seen by public health officials as a global tobacco epidemic. Cigarette Environmental Tobacco Smoke (ETS) is classically understood as a combination of Side-Stream Smoke (SSS) and Exhaled Main-Stream Smoke (EMSS), both diluted and aged. Some of the corresponding cigarette studies have served as the scientific basis for stringent legislation on indoor smoking across the world. Interestingly, one of the distinctive traits of the hookah device is that it generates almost no SSS. Indeed, its ETS is made up almost exclusively by the smoke exhaled by the smoker (EMSS), i.e. which has been filtered by the hookah at the level of the bowl, inside the water, along the hose and then by the smoker’s respiratory tract itself. The present paper reviews the sparse and scattered scientific evidence available about hookah EMSS and the corresponding inferences that can be drawn from the composition of cigarette EMSS. The reviewed literature shows that most of hookah ETS is made up of EMSS and that the latter qualitatively differs from MSS. Keeping in mind that the first victim of passive smoking is the active smoker her/himself, the toxicity of hookah ETS for non-smokers should not be overestimated and hyped in an unscientific way. En ligne : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672364/ Format de la ressource électronique : HTML, PDF Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=7989 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : Periodontal health status in adults exposed to tobacco heating system aerosol and cigarette smoke vs. non-smokers: a cross-sectional study Type de document : document électronique Auteurs : Ivana Miškovi´c, Auteur ; Davor Kuiš, Auteur ; Stjepan Špalj, Auteur Editeur : Bâle [Suisse] : MDPI AG (Molecular Diversity Preservation International) Année de publication : 2024 Collection : Dentistry journal num. 12:26 Importance : 13 p. Présentation : tab., graph. Langues : Anglais (eng) Catégories : [DIVERS] personne:par âge:adulte
[TABAC] CANDIDATS:e-cigarette
[TABAC] chimie du tabac:constituant:alcaloïde:nicotine
[TABAC] étude:recherche
[TABAC] tabagisme:effet du tabac:effet bucco-dentaire
[TABAC] tabagisme:tabagisme passif:non-fumeurIndex. décimale : TA 1.1.1 Cigarettes (« normales », électroniques, aromatisées,…) Résumé : Tobacco heating systems (THS) are new products on the market, advertised as a less harmful alternative for smokers, in which tobacco is heated and not burned like in conventional cigarettes. This research explored the effect on periodontal tissues in contact with heating and burning tobacco residual products (smoke and tobacco).
Methods:
The sample included 66 subjects, patients of the Clinic of Dentistry in Rijeka, Croatia, aged 26–56 (median 38), 64% females. Three age- and
gender-matched groups were formed (each N = 22): non-smokers, classic cigarettes smokers and THS smokers. Probing depth (PD) and clinical attachment loss (CAL) were primary research parameters.
Results:
Three groups differed in average PD and CAL (p ≤ 0.002), with cigarette smokers having the highest and non-smokers the lowest values (p ≤ 0.002). THS consumers generally had lower values of periodontal indices than smokers, but only CAL differed significantly (p = 0.011). Periodontal indices CAL and PD were worse in THS consumers than non-smokers, but they did not reach a level of statistical significance. Cigarette smoking was the only predictor of periodontitis (average
CAL ≥ 4 mm) in logistic regression models, with an odds ratio of 4.7 (95% confidence interval 1.2–18.3; p = 0.027).
Conclusions:
Exposure to nicotine-containing aerosol of THS in adults has a less harmful effect on periodontal tissues, measurable through periodontal indices (PD and CAL),
compared to burning tobacco of conventional cigarettes. THS, presented as an alternative product to classic cigarettes, also has a detrimental effect on the periodontium.En ligne : https://doi.org/10.3390/dj12020026 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10313 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : Personality risk factors for vape use amongst young adults and its consequences for sleep and mental health Type de document : document électronique Auteurs : Simon, L. Evans, Auteur ; Erkan Alkan, Auteur Editeur : Bâle [Suisse] : MDPI AG (Molecular Diversity Preservation International) Année de publication : 2024 Collection : Healthcare num. 12:423 Importance : 12 p. Présentation : tab. Langues : Anglais (eng) Catégories : [DIVERS] géographie:Europe:Europe occidentale:Royaume-Uni
[DIVERS] personne:par âge:jeune
[TABAC] CANDIDATS:e-cigarette
[TABAC] prévention:santé:santé mentale
[TABAC] sevrage tabagique:effet du sevrage:anxiété
[TABAC] tabagisme:effet du tabac:effet psychiatrique:dépressionMots-clés : sommeil Index. décimale : TA 3.2 Effets du tabagisme actif Résumé : Background: The surge in vape (e-cigarette) use among young adults is concerning, as there is limited knowledge about risk factors and health consequences. This study explores the personality traits linked to vape use, and associations between vaping and chronotype, sleep quality, and mental health, among young adults. (2)
Methods: 316 participants, aged 18–25, completed measurements of mindfulness, rumination, self-compassion, anxiety/depression, chronotype, and sleep quality. (3)
Results: the vape user group scored significantly lower on mindfulness, higher on rumination, and lower on self-compassion. Vape users were more likely to be evening types and had significantly lower sleep quality and higher anxiety symptoms, as well as higher alcohol use and loneliness (at trend) (4)
Conclusions: These novel findings enhance our understanding of what might predispose young adults to vaping and the potential impact on their mental health and sleep
quality. Findings point to specific cognitive/personality traits as vaping risk factors, which could inform intervention strategies.
Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10200 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : The health effects of real-world dual use of electronic and conventional cigarettes versus the health effects of exclusive smoking of conventional cigarettes : systematic review Type de document : document électronique Auteurs : Charlotta Pisinger, Auteur ; Sofie, K Bergman Rasmussen, Auteur Editeur : Bâle [Suisse] : MDPI AG (Molecular Diversity Preservation International) Collection : International Journal of Environmental Research and Public Health, ISSN 1660-4601 num. 19 Importance : 23 p. Présentation : tab. Langues : Français (fre) Catégories : [TABAC] chimie du tabac:tabac fumé:cigarette
[TABAC] chimie du tabac:tabac fumé:cigarette:cigarette électronique
[TABAC] étude
[TABAC] tabagisme:effet du tabac
[TABAC] tabagisme:tabagisme actifMots-clés : revue de la littérature
consommations associéesIndex. décimale : TA 1.1.1 Cigarettes (« normales », électroniques, aromatisées,…) Résumé : Background:
A high prevalence of dual use of e-cigarettes and conventional cigarettes has been reported across the world.
Methods:
A systematic search was carried out. We included original
articles on any topic relevant to health, excluding mental health, in all languages. The PRISMA guidelines were followed. Both reviewers independently screened and read all publications. We
compared dual use with exclusive smoking of conventional cigarettes (ESCC).
Results:
Fifty-two publications (49 studies) were included. Thirteen papers/10 studies were prospective. There was great heterogeneity across studies. Many methodological weaknesses, such as inaccurate exposure measurement, lack of adjustment for former tobacco consumption, and lack of significance testing were identified. Most prospective studies found dual use to be at least as harmful as ESCC. The longest follow-up was six years. Most of the best available cross-sectional studies found dual use associated with the same and, in several studies, significantly higher risk of self-reported symptoms/disease than in ESCC. The intensity of cigarette smoking seems associated with worse health.
Conclusion:
Existing studies indicate that dual use is at least as, or probably even more, harmful than ESCC. Due to the predominance of cross-sectional studies and the methodological weaknesses we judged the overall certainty of the evidence as “low certainty”.Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=9840 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : Third-hand exposure to e-cigarette vapour induces pulmonary efects in mice Type de document : document électronique Auteurs : Andrew E. Thorpe, Auteur ; Chantal Donovan, Auteur ; Richard Y. Kim, Auteur ; Howard J. Vindin, Auteur ; Razia Zakarya, Auteur Editeur : Bâle [Suisse] : MDPI AG (Molecular Diversity Preservation International) Année de publication : 2023 Collection : Toxics num. 11:749 Importance : 12 p. Présentation : graph., tab., ill. Langues : Anglais (eng) Catégories : [TABAC] CANDIDATS:e-cigarette
[TABAC] chimie du tabac:constituant:alcaloïde:nicotineMots-clés : Expérimentation animale Index. décimale : TA 3.2.2.4 Pathologies respiratoires (sauf 3.2.2.1, 3.2.2.2, 3.2.2.3) Résumé : In the last decade, e-cigarette usage has increased, with an estimated 82 million e-cigarette users globally. This is, in part, due to the common opinion that they are “healthier” than tobacco cigarettes or simply “water vapour”. Third-hand e-vapour exposure is the chemical residue left behind from e-cigarette aerosols, which is of concern due to its invisible nature, especially among young children. However, there is limited information surrounding third-hand e-vapour exposure.
This study aimed to investigate the pulmonary effects of sub-chronic third-hand e-vapour exposure in a murine model. BALB/c mice (4 weeks of age) were exposed to a towel containing nicotine free (0 mg) e-vapour, nicotine (18 mg) e-vapour, or no e-vapour (sham) and replaced daily for 4 weeks. At the endpoint, lung function was assessed, and bronchoalveolar lavage fluid and lungs were collected to measure inflammation and fibrosis. Mice exposed to third-hand e-vapour without nicotine had alveolar enlargement compared to sham exposed controls. Mice exposed to third-hand e-vapour with nicotine had reduced bronchial responsiveness to provocation, increased epithelial thickening in large airways, increased epithelial layers in small airways, alveolar enlargement, and increased small airway collagen deposition, compared to sham exposed controls. In conclusion, our study shows that third-hand e-vapour exposure, particularly in the presence of nicotine, negatively affects the lung health of mice and highlights the need for greater public awareness surrounding the dangers of third-hand exposure to e-cigarette vapour.
Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10217 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : Vaping-dependent pulmonary inflammation is Ca2+ mediated and potentially sex specific Type de document : document électronique Auteurs : Jeffrey G Shipman, Auteur ; Rob U. Onyenwoke, Auteur ; Vijay Sivaraman, Auteur Editeur : Bâle [Suisse] : MDPI AG (Molecular Diversity Preservation International) Année de publication : 2024 Collection : International journal of molecular sciences num. 25 Importance : 12 p. Présentation : ill., tab., graph. Langues : Anglais (eng) Catégories : [TABAC] CANDIDATS:e-cigarette
[TABAC] tabagisme:pathologie:pathologie respiratoire:coeur pulmonaireMots-clés : expérimentation animale Index. décimale : TA 1.1.1 Cigarettes (« normales », électroniques, aromatisées,…) Résumé : Here we use the SCIREQ InExpose system to simulate a biologically relevant vaping model in mice to investigate the role of calcium signaling in vape-dependent pulmonary disease as well as to investigate if there is a gender-based difference of disease. Male and female mice were vaped with JUUL Menthol (3% nicotine) using the SCIREQ InExpose system for 2 weeks. Additionally, 2-APB, a known calcium signaling inhibitor, was administered as a prophylactic for lung disease and damage caused by vaping. After 2 weeks, mice were exposed to lipopolysaccharide (LPS) to mimic a bacterial infection. Post-infection (24 h), mice were sacrificed, and bronchoalveolar lavage fluid (BALF) and lungs were taken. Vaping primed the lungs for worsened disease burden after microbial challenge (LPS) for both males and females, though females presented increased neutrophilia and inflammatory cytokines post-vape compared to males, which was assessed by flow cytometry, and cytokine and histopathological analysis. This increased inflammatory burden was controlled by calcium signaling inhibition, suggesting that calcium dysregulation may play a role in lung injury caused by vaping in a gender-dependent manner. En ligne : https://doi.org/ 10.3390/ijms25031785 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10309 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
