| Titre : |
Automated detection of controlled substances from sealed e-cigarettes |
| Type de document : |
document électronique |
| Auteurs : |
Matthew Gardner, Auteur ; Celeste Bowden, Auteur ; Shoaib Manzoor, Auteur |
| Editeur : |
American Chemical Society (ACS) |
| Année de publication : |
2024 |
| Collection : |
Analytical Chemistry, ISSN 2573-2293 |
| Importance : |
10 p. |
| Présentation : |
ill., graph. |
| Langues : |
Anglais (eng) |
| Catégories : |
[DIVERS] géographie:Europe:Europe occidentale:Royaume-Uni
[TABAC] chimie du tabac
[TABAC] chimie du tabac:tabac fumé:cigarette:cigarette électronique
[TABAC] étude
[TABAC] tabagisme:effet du tabac:toxicité
[TABAC] tabagisme:risque
[TABAC] tabagisme:risque:facteur associé:drogue
[TABAC] tabagisme:risque:facteur associé:drogue:cannabis
|
| Index. décimale : |
TA 0.7 Autres drogues |
| Résumé : |
Synthetic cannabinoids (SCs) are novel psychoactive substances (NPS)that are highly potent and associated with a range of severe toxicities. SC use, which is common in UK prisons and homeless communities, typically involves combustion of SC-soaked herb or paper material. Recently, e-cigarettes (or vapes) have emerged as popular delivery vehicles for SCs, and consumption amongst the general population has risen significantly. SC-containing e-cigarettes (or e-liquids) are sold through street dealers or on the black market, often as imitation cannabis extracts, where both compound and concentration are un?specified. The risk of SC toxicity due to accidental consumption is therefore high. Numerous overdoes tied to SC-containing e?cigarettes have been reported in schools around the UK, where side effects include psychosis, seizure and cardiac arrest. SCs cannot be identified in complex e-liquid matrices using current field-portable detection technologies, preventing the rapid screening of suspicious products. Herein, we report on the design and development of a device that can rapidly detect SCs and other relevant drugs in sealed e-cigarettes and e-liquids. We describe and implement a method to artificially actuate an e-cigarette, simultaneously depositing e-liquid vapor onto a physical matrix. We couple this extraction method with fluorescence-based detection of SCs to create a rapid and generic test for SC-containing e-cigarettes. In addition, we expand the potential of the detection modality by leveraging the photochemical degradation of THC and nitazenes on a solid matrix as a means for their rapid detection from e-liquids and sealed e-cigarettes. |
| En ligne : |
https://doi.org/10.26434/chemrxiv-2024-ns335 |
| Format de la ressource électronique : |
Article en ligne |
| Permalink : |
https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10481 |
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Automated detection of controlled substances from sealed e-cigarettes (2024)
