| Titre : |
Pharmacokinetics, safety, and tolerability of varenicline in healthy adolescent smokers : a multicenter, randomized, double-blind, placebo-controlled, parallel-group study |
| Type de document : |
texte imprimé |
| Auteurs : |
Helene Faessel, Auteur ; Patanjali Ravva, Auteur ; Kathryn Williams, Auteur |
| Editeur : |
Excerpta Medica Inc. |
| Année de publication : |
2009 |
| Collection : |
Clinical Therapeutics num. 31 (1) |
| Importance : |
p.177-189 |
| Note générale : |
Dans la bibliothèque virtuelle (articles scientifiques) |
| Langues : |
Anglais (eng) |
| Catégories : |
[DIVERS] discipline médicale, paramédicale et scientifique:pharmacologie
[DIVERS] personne:famille:adolescent
[TABAC] étude
[TABAC] sevrage tabagique
[TABAC] sevrage tabagique:méthode de sevrage:méthode individuelle:approche pharmacologique:varénicline
|
| Index. décimale : |
TA 6.2.3.1.4 Autres substituts nicotiniques |
| Résumé : |
Conclusions: Varenicline steady-state exposure in study subjects weighing >55 kg was similar to that observed previously in adults. The body-weight effect on varenicline pharmacokinetics, which resulted in higher exposure in individuals of smaller body size (<::55 kg), was adequately offset by administration of half the varenicline dose recommended in adults. Varenicline was generally well tolerated during the 14-day treatment period. |
| En ligne : |
https://doi.org/10.1128%2Faac.42.8.2060 |
| Format de la ressource électronique : |
Article en ligne |
| Permalink : |
https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=2709 |
Pharmacokinetics, safety, and tolerability of varenicline in healthy adolescent smokers (2009)
