| Titre : |
Magnitude of Mycobacterium tuberculosis transmission among household and non-household contacts of TB patients |
| Type de document : |
document électronique |
| Auteurs : |
M. Kato-Maeda, Auteur ; J.C. Choi, Auteur ; L.G. Jarlsberg, Auteur |
| Editeur : |
International Union Against Tuberculosis and Lung Disease (IUATLD) |
| Année de publication : |
2019 |
| Collection : |
International Journal of Tuberculosis and Lung Disease num. 23(4) |
| Importance : |
p.433-440 |
| Langues : |
Anglais (eng) |
| Catégories : |
[DIVERS] personne:famille
[TUBER] cause:contagion
[TUBER] étude:épidémiologie
|
| Index. décimale : |
TU 3.7.1. Entourage |
| Résumé : |
SETTING: The household and non-household contacts of patients with tuberculosis (TB) face varying degrees of risk of infection by Mycobacterium tuberculosis.
OBJECTIVE: To quantify new infection and to determine the risk factors associated with new infection among named contacts in San Francisco, CA, USA.
DESIGN: We performed a cohort study in patients with culture-positive pulmonary TB. We analyzed patient, contact, environmental and bacterial characteristics.
RESULTS: Of the 2422 contacts named by 256 patients, 149 (6.2%) had new infection due to recent transmission from 79 (30.9%) patients. Of the 149 new infections, 87 (58.4%) occurred among household contacts and 62 (41.6%) among non-household contacts. Numerous acid-fast bacilli in sputum (odds ratio [OR] 2.64, 95%CI 1.32–5.25) and contacts being named by more than one patient (OR 2.90, 95%CI 1.23–6.85) were associated with new infection among household contacts. Being older than 50 years (OR 1.93, 95%CI 1.09–3.41) and an Asian/Pacific Islander (OR 3.09, 95%CI 1.50–6.37) were associated with new infection among non-household contacts.
CONCLUSIONS: Fewer than one third of patients caused new infection to his/her contacts. A substantial proportion of transmission resulting in new infection occurred outside of the household. The risk factors for infection among household and non-household contacts are different and should be considered when prioritizing control interventions. |
| En ligne : |
https://doi.org/10.5588/ijtld.18.0273 |
| Format de la ressource électronique : |
Article en ligne |
| Permalink : |
https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10026 |
Ajouter le résultat dans votre panier Affiner la rechercheMagnitude of Mycobacterium tuberculosis transmission among household and non-household contacts of TB patients / M. Kato-Maeda (2019)
