Physical and chemical characterizations of a reference e‑cigarette used in animal testing / Sébastien Soulet (2023)  

Public Titre : Physical and chemical characterizations of a reference e‑cigarette used in animal testing Type de document : document électronique Auteurs : Sébastien Soulet, Auteur ; Léa Constant, Auteur ; Vanille Quinty, Auteur Editeur : Springer Nature Année de publication : 2023 Collection : Scientific Reports Importance : 10 p. Présentation : graph. Langues : Anglais (eng) Catégories : [TABAC] CANDIDATS:e-cigarette [TABAC] chimie du tabac:tabac fumé:cigarette:cigarette électronique [TABAC] étude Mots-clés : Expérimentation animale :-( caractéristiques physiques... du produit Index. décimale : TA 1.1.1 Cigarettes (« normales », électroniques, aromatisées,…) Résumé : A minimal necessary condition for preclinical studies to contribute to risk assessments of e-cigarettes (ECs) is the ability to expose laboratory animals to an appropriate dosage of aerosols. In this study, we examined the fulfilment of this essential consistency condition for the ECX-Joyetech E-Vic Mini (ECX),a piece of computerized exposure equipment manufactured by SCIREQ, which has been employed by numerous in vivo testing. We began by calibrating the customary Evic VTC mini device mod and the 4 coils available, reproducing in the laboratory the operation of the ECX in the power-control and temperature-control modes, using puffing parameters recommended by its documentation. We then conducted the following tests for each coil: (1) verifying whether the generated aerosols satisfy an optimal operational regime, free from overheating, as determined by a linear relation between the mass of vaporized e-liquid vs. supplied power and (2) obtaining the mean yields of aldehydes for each of the tested power settings and coils. The results of these tests show that, under the main conditions used in in vivo testing, the ECX equipment fails to comply with these consistency requirements, especially for coils with low subohm resistance, a shortcoming that can be corrected by applying much larger airflows for these coils. Therefore, the outcomes of preclinical studies using the ECX equipment should be examined with great scepticism and subjected to further testing. En ligne : https://doi.org/10.1038/s41598-023-43733-3 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10255

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Thermal engineering of electronic cigarettes / Sébastien Soulet (2023)  

Public Titre : Thermal engineering of electronic cigarettes Type de document : document électronique Auteurs : Sébastien Soulet, Auteur ; Carine Casile, Auteur Editeur : New-York [États-Unis] : Elsevier Science Année de publication : 2023 Collection : Case Studies in Thermal Engineering, Importance : 22 p. Présentation : ill, tab., graph Langues : Anglais (eng) Catégories : [TABAC] CANDIDATS:e-cigarette [TABAC] tabagisme:risque Mots-clés : e-liquide, expérimentation, mécanique, physique Index. décimale : TA 1.1.1 Cigarettes (« normales », électroniques, aromatisées,…) Résumé : Electronic cigarettes were developed to vaporise an e-liquid containing nicotine. In addition to chemical composition, health and safety risks are associated with the power supply. The aim of this study was to determine the functioning limits using boiling correlations for the onset of nucleate boiling and critical-heat flux. These estimations are in contrast with the experimentally obtained values. To achieve this, forty-six atomisers were used and filled with a standardized e-liquid. The emissions were generated by supplying different power ratings, starting with a low power, which was increased for each new experiment until a malfunction occurred. The influence is characterised by the mass of the vaporised e-liquid (mass difference of the atomiser before and after the experiment). The results showed good agreement (33% and 19% in absolute deviations, 14% and -1% in relative deviations) between the boiling correlations (Sato and Matsumara, Zuber) and the functional limit of an E-cigarette. This link establishes how an E-cigarette is controlled through boiling. Determining the functional curve of a device should be a standardised requirement to show its physical limitations and would be a major contributor to reducing the risk of device use. En ligne : https://doi.org/10.1016/j.csite.2023.103512 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10235

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