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Titre : Electronic cigarette use in youths : a position statement of the Forum of International Respiratory Societies Type de document : document électronique Auteurs : Thomas W. Ferkol, Auteur ; Harold J. Farber, Auteur ; Stefania La Grutta, Auteur Editeur : European Respiratory Society (ERS) Année de publication : 2018 Collection : European Respiratory Journal Importance : 9 p. Langues : Anglais (eng) Catégories : [DIVERS] personne:famille:adolescent
[DIVERS] personne:famille:enfant
[TABAC] chimie du tabac:constituant:alcaloïde:nicotine
[TABAC] chimie du tabac:tabac fumé:cigarette:cigarette électronique
[TABAC] prévention:recommandation
[TABAC] tabagisme:effet du tabac:effet neurologiqueIndex. décimale : TA 1.1.1 Cigarettes (« normales », électroniques, aromatisées,…) Résumé : Children and adolescents are highly susceptible to nicotine addiction, which affects their brain development, even in those who smoke infrequently. Young people who become addicted to nicotine are at greater risk of becoming lifelong tobacco consumers. The use of nicotine-delivering electronic cigarettes has risen dramatically among youths worldwide. In addition to physical dependence, adolescents are susceptible to social and environmental influences to use electronic cigarettes. The product design, flavours, marketing, and perception of safety and acceptability have increased the appeal of electronic cigarettes to young people, thus leading to new generations addicted to nicotine. Moreover, there is growing evidence that electronic cigarettes in children and adolescents serve as a gateway to cigarette
smoking. There can be no argument for harm reduction in children. To protect this vulnerable population from electronic cigarettes and other nicotine delivery devices, we recommend that electronic cigarettes be regulated as tobacco products and included in smoke-free policies. Sale of electronic cigarettes should be
barred to youths worldwide. Flavouring should be prohibited in electronic cigarettes, and advertising accessible by youths and young adults be banned. Finally, we recommend greater research on the health effects of electronic cigarettes and surveillance of use across different countries.En ligne : https://doi.org/10.1183/13993003.00278-2018 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=9737 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Forecasting vaping health risks through neural network model prediction of flavour pyrolysis reactions / Akihiro Kishimoto (2024)
Titre : Forecasting vaping health risks through neural network model prediction of flavour pyrolysis reactions Type de document : document électronique Auteurs : Akihiro Kishimoto, Auteur ; Dan Wu, Auteur ; Donal F. O’Shea, Auteur Editeur : Springer Nature Année de publication : 2024 Collection : Scientific Reports num. 14 Importance : 14 p. Présentation : graph., tab., ill. Langues : Anglais (eng) Catégories : [TABAC] CANDIDATS:e-cigarette
[TABAC] chimie du tabac
[TABAC] chimie du tabac:constituant:additif:agent de saveur
[TABAC] tabagisme:effet du tabac:effet neurologiqueMots-clés : e-liquide Index. décimale : TA 1.1.1 Cigarettes (« normales », électroniques, aromatisées,…) Résumé : Vaping involves the heating of chemical solutions (e-liquids) to high temperatures prior to lung inhalation. A risk exists that these chemicals undergo thermal decomposition to new chemical
entities, the composition and health implications of which are largely unknown. To address this concern, a graph-convolutional neural network (NN) model was used to predict pyrolysis reactivity
of 180 e-liquid chemical flavours. The output of this supervised machine learning approach was a dataset of probability ranked pyrolysis transformations and their associated 7307 products. To refine this dataset, the molecular weight of each NN predicted product was automatically correlated with experimental mass spectrometry (MS) fragmentation data for each flavour chemical. This blending of deep learning methods with experimental MS data identified 1169 molecular weight matches that prioritized these compounds for further analysis. The average number of discrete matches per flavour between NN predictions and MS fragmentation was 6.4 with 92.8% of flavours having at least one match. Globally harmonized system classifications for NN/MS matches were extracted
from PubChem, revealing that 127 acute toxic, 153 health hazard and 225 irritant classifications were predicted. This approach may reveal the longer-term health risks of vaping in advance of clinical diseases emerging in the general population.En ligne : https://doi.org/10.1038/s41598-024-59619-x Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10289 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : Nicotine addiction and nicotinic receptors : lessons from genetically modified mice Type de document : texte imprimé Auteurs : Jean-Pierre Changeux, Auteur Editeur : Macmillan Editions Année de publication : 2010 Collection : Nature Neuroscience, ISSN 1097-6256 Importance : p.389-401 Langues : Français (fre) Catégories : [TABAC] chimie du tabac:constituant:alcaloïde:nicotine:récepteur nicotinique
[TABAC] tabagisme:aspect psychologique:comportement:addiction
[TABAC] tabagisme:effet du tabac:effet neurologiqueIndex. décimale : TA 1.3 Nicotine Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=7433 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : Nicotine use among children and young people : consequences and prevention Type de document : document électronique Auteurs : Jørgen Vestbo, Auteur ; Jesper Tobias Andreasen, Auteur ; Lotus Sofie Bast, Auteur ; Lisbeth Lund, Auteur ; Charlotta Pisinger, Auteur Editeur : The Council on Health and Disease Prevention Année de publication : 2023 Importance : 50 p. Présentation : graph., tab., ill. ISBN/ISSN/EAN : 978-87-971490-7-2 Langues : Anglais (eng) Langues originales : Danois (dan) Catégories : [DIVERS] géographie:Europe:Europe du Nord:Danemark
[DIVERS] personne:famille:enfant
[DIVERS] personne:par âge:jeune
[TABAC] CANDIDATS:e-cigarette
[TABAC] CANDIDATS:snuss
[TABAC] chimie du tabac:constituant:alcaloïde:nicotine
[TABAC] chimie du tabac:tabac non fumé
[TABAC] prévention
[TABAC] tabagisme:dépendance tabagique
[TABAC] tabagisme:effet du tabac:effet neurologique
[TABAC] tabagisme:risque:facteur associé:drogue
[TABAC] tabagisme:tabagisme actifIndex. décimale : TA 5.1 Théorie Résumé : The number of children and young people who consume smokeless nicotine products has increased considerably in the past 5-10 years. Today, children and young people are exposed
to a growing selection of nicotine products, including e-cigarettes, pouches, Swedish snus and chewing tobacco among others. The ample selection of available nicotine products in conjunction with their low price compared with cigarettes, the taste additives used and a packing that appeals to children and young people may be attractive to these groups and contribute to their rising popularity.
In view of the increasing consumption of this addictive drug among children and young people, the National Centre for Health Promotion and Prevention perceives that with this report we meet a need to present current research-based knowledge about the consequences of nicotine consumption for the health and wellbeing of children and young people. Additionally, the report summarises knowledge about tobacco prevention with the aim of strengthening the decision basis for preventive measures targeting nicotine consumption.
Prevalence of nicotine products
In Denmark, around one in every three (31%) children and young people aged 15-29 years consume some type of nicotine products daily or occasionally. Excluding consumption of cigarettes
from the figures, 14.7% of children and young people consume nicotine products. In other words, around half of the children and young people who consume nicotine products only use other nicotine products than cigarettes. Among the smoke-free nicotine products, the more prevalent ones are Swedish snus and nicotine pouches.
Health risks
Among the harmful effects of nicotine for children and young people’s health, the effect on the development of the brain is particularly worrying. The human brain is not fully developed until around 25-30 years of age, and use of nicotine at a young age has various negative effects on the development of the brain.
Dependence and addiction: Nicotine is an appealing substance because it has an energizing effect and elevates mood. Furthermore, it is one of the most addictive drugs known.
Gateway effect: Based on current research originating from human and animal studies, The Working Group assesses that moderate to strong evidence supports that nicotine increases
the likelihood of becoming addicted to cigarettes and drugs in general. Thus, nicotine seems to
have a so-called ‘gateway’ effect.En ligne : https://vidensraad.dk/sites/default/files/paragraph/field_download/vff_nicotine_ [...] Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10215 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : Smoking, tobacco dependence, and neurometabolites in the dorsal anterior cingulate cortex Type de document : document électronique Auteurs : Joseph O'Neill, Auteur ; Maylen Perez Diaz, Auteur ; Jeffry R. Alger, Auteur ; Jean-Baptiste Pochon, Auteur Editeur : Springer Nature Année de publication : 2023 Collection : Molecular Psychiatry Importance : 10 p. Présentation : tab., ill., graph. Langues : Anglais (eng) Catégories : [DIVERS] anatomie:corps humain:système nerveux:cerveau
[TABAC] tabagisme:effet du tabac:effet neurologiqueIndex. décimale : TA 3.2.2.6 Effets métaboliques et biologiques Résumé : Cigarette smoking has a major impact on global health and morbidity, and positron emission tomographic research has provided evidence for reduced inflammation in the human brain associated with cigarette smoking. Given the consequences of inflammatory dysfunction for health, the question of whether cigarette smoking affects neuroinflammation warrants further investigation.
The goal of this project therefore was to validate and extend evidence of hypoinflammation related to smoking, and to examine the potential contribution of inflammation to clinical features of smoking. Using magnetic resonance spectroscopy, we measured levels of neurometabolites that are putative neuroinflammatory markers. N-acetyl compounds (N-acetylaspartate + Nacetylaspartylglutamate), glutamate, creatine, choline-compounds (phosphocholine + glycerophosphocholine), and myo-inositol, have all been linked to neuroinflammation, but they have not been examined as such with respect to smoking. We tested whether people who smoke cigarettes have brain levels of these metabolites consistent with decreased neuroinflammation, and whether clinical features of smoking are associated with levels of these metabolites. The dorsal anterior cingulate cortex was chosen as the region-of-interest because of previous evidence linking it to smoking and related states.
Fifty-four adults who smoked daily maintained overnight smoking abstinence before testing and were compared with 37 nonsmoking participants. Among the smoking participants, we tested for associations of metabolite levels with tobacco dependence, smoking history, craving, and withdrawal. Levels of N-acetyl compounds and glutamate were higher, whereas levels of creatine and choline compounds were lower in the smoking group as compared with the nonsmoking group. In the smoking group, glutamate and creatine levels correlated negatively with tobacco dependence, and creatine correlated negatively with lifetime smoking, but none of the metabolite levels correlated with craving or withdrawal. The findings indicate a link between smoking and a hypoinflammatory state in the brain, specifically in the dorsal anterior cingulate cortex. Smoking may thereby increase vulnerability to infection and brain injury.
En ligne : https://doi.org/10.1038/s41380-023-02247-0 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10259 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : Vaping and the brain : effects of electronic cigarettes and e-liquid substances Type de document : document électronique Auteurs : Wilfredo López-Ojeda, Auteur ; Robin A. Hurley, Auteur Editeur : American Psychiatric Association Année de publication : 2024 Collection : The journal of neuropsychoiatry and clincal neurosciences num. 36:1 Importance : 6 p. Présentation : ill. Langues : Anglais (eng) Catégories : [TABAC] CANDIDATS:e-cigarette
[TABAC] chimie du tabac:constituant:additif
[TABAC] chimie du tabac:constituant:additif:agent de saveur
[TABAC] tabagisme:effet du tabac:effet neurologique
[TABAC] tabagisme:effet du tabac:toxicité
[TABAC] tabagisme:tabagisme passifMots-clés : e-liquide Index. décimale : TA 1.1.1 Cigarettes (« normales », électroniques, aromatisées,…) Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10178 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
