| Titre : |
Sponteanous preterm birth and small for gestational age infants in women who stop smoking early in pregnancy : prospective cohort study |
| Type de document : |
texte imprimé |
| Auteurs : |
Lesley M.E McCowan, Auteur ; Gustaaf A Dekker, Auteur ; Eliza Chan, Auteur |
| Editeur : |
BMJ Publishing Group |
| Année de publication : |
2009 |
| Importance : |
6 p. |
| Langues : |
Anglais (eng) |
| Catégories : |
[TABAC] étude
[TABAC] tabagisme:risque:facteur associé:grossesse
|
| Index. décimale : |
TA 3.2.2.7 Grossesse et fœtus |
| Résumé : |
Objectives : To compare pregnancy outcomes between women who stopped smoking in early pregnancy and those who either did not smoke in pregnancy or continued to smoke.
Design : Prospective cohort study.
Setting : Auckland, New Zealand and Adelaide, Australia.
Participants : 2504 nulliparous women participating in the Screening for Pregnancy Endpoints (SCOPE) study grouped by maternal smoking status at 15 (±1) week’s gestation.
Main outcome measures : Spontaneous preterm birth and small for gestational age infants (birth weight <10th customised centile). We compared odds of these outcomes between stopped smokers and non-smokers, and between current smokers and stopped smokers, using logistic regression, adjusting for demographic and clinical risk factors.
Results : 80% (n=1992) of women were non-smokers, 10% (n=261) had stopped smoking, and 10% (n=251) were current smokers. We noted no differences in rates of spontaneous preterm birth (4%, n=88 v 4%, n=10; adjusted odds ratio 1.03, 95% confidence interval l0.49 to 2.18; P=0.66) or small for gestational age infants (10%, n=195 v 10%, n=27; 1.06, 0.67 to 1.68; P=0.8) between non-smokers and stopped smokers. Current smokers had higher rates of spontaneous preterm birth (10%, n=25 v 4%, n=10; 3.21, 1.42 to 7.23; P=0.006) and small for gestational age infants (17%, n=42 v 10%, n=27; 1.76, 1.03 to 3.02; P=0.03) than stopped smokers.
Conclusion : In women who stopped smoking before 15 weeks’ gestation, rates of spontaneous preterm birth and small for gestational age infants did not differ from those in non-smokers, indicating that these severe adverse effects of smoking may be reversible if smoking is stopped early in pregnancy. |
| En ligne : |
https://www.bmj.com/content/338/bmj.b1081 |
| Permalink : |
https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=7504 |
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Sponteanous preterm birth and small for gestational age infants in women who stop smoking early in pregnancy (2009)
