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Ajouter le résultat dans votre panier Affiner la rechercheAn investigation into the association between ecigarette smoking and oral mucosal health status among young people / Siyuan Cheng (2023)
Titre : An investigation into the association between ecigarette smoking and oral mucosal health status among young people : protocol for a case control trial Type de document : document électronique Auteurs : Siyuan Cheng, Auteur Editeur : Toronto [Canada] : Journal of Medical Internet Research - JMIR Année de publication : 2023 Collection : JMIR Research Protocols, ISSN 1929-0748 Importance : 18 p. Langues : Anglais (eng) Catégories : [DIVERS] personne:par âge:jeune
[TABAC] chimie du tabac:tabac fumé:cigarette
[TABAC] étude
[TABAC] tabagisme:effet du tabac:effet bucco-dentaire
[TABAC] tabagisme:pathologie:pathologie bucco-dentaire
[TABAC] tabagisme:tabagisme passif:non-fumeurIndex. décimale : TA 3.2.2.6 Effets métaboliques et biologiques Résumé : Background:
Given the paucity of current safety studies related to e-cigarettes, there are no definitive studies on whether e-cigarettes cause oral mucosal lesions or even oral cancer. Although it is still undetermined whether e-cigarettes are harmless, an increasing number of teenagers choose to smoke e-cigarettes and believe that they are not harmful to the human body.
Objective:
This aims to determine whether e-cigarettes cause damage to the oral mucosa. This study also aims to evaluate the association between e-cigarette smoking and oral mucous membrane lesions in young adults. The objectives are to (1) compare the oral mucosal conditions in participants with and without e-cigarette smoking habits, (2) assess the effect of the amount of e-cigarette smoking on oral mucosal conditions, and (3) assess the effect of the duration of e-cigarette smoking on oral mucosal conditions.
Methods:
In this prospective study, 304 youths aged 15 to 24 years (n=152, 50% who smoke only e-cigarettes and n=152, 50% who do not smoke e-cigarettes or cigarettes) will be divided into 2 groups for a controlled study. Whether e-cigarettes cause oral mucosal lesions will be verified by comparing the odds of oral mucosal lesions in the 2 experimental groups. For this experiment, the predefined power is 80% (P=.04), and the predefined proportions of groups 1 and 2 are 11% and 2.5%, respectively.
Results:
This experiment is at the conceptualization phase and has not yet been carried out. Experimenters have not been recruited and no data have been collected.
Conclusions:
e-Cigarettes are still an unfamiliar topic to the public, and it is still unknown whether they can cause damage to the oral mucosa. This experiment aims to find out whether there is a link between the 2. There are still many limitations in this study, such as the lack of categorization of e-cigarettes and the lack of testing methods for oral mucosal status. These limitations are expected to be addressed in the future as the experiment is formally conducted and further optimized.En ligne : https://doi.org/10.2196/53644 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10555 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : Embrassez un non-fumeur, goûtez la différence ! Type de document : texte imprimé Auteurs : Jean-Paul Van Vooren, Directeur de publication ; Nathalie Da Costa Maya, Illustrateur Editeur : Ixelles [Belgique] : Fonds des Affections Respiratoires (FARES) asbl Année de publication : 2013 Importance : 6 p. Langues : Français (fre) Catégories : [TABAC] sevrage tabagique:aide au sevrage
[TABAC] tabagisme:effet du tabac:effet bucco-dentaire
[TABAC] tabagisme:pathologie:pathologie bucco-dentaire
[TABAC] tabagisme:risqueRésumé : Dépliant centré sur les effets du tabac et la santé buccale, réalisé en collaboration avec la Société de Médecine Dentaire En ligne : http://www.fares.be/static/upload/1/2/depliant_dentistes.pdf Format de la ressource électronique : Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=7540 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : The exposomal impacts of e-cigarettes on the oral microbiome Type de document : document électronique Auteurs : Michelle Lee-Scott Beverly, Auteur Editeur : Ohio State University Année de publication : 2024 Importance : 158 p. Présentation : ill., graph.; tab Langues : Anglais (eng) Catégories : [DIVERS] discipline médicale, paramédicale et scientifique:biologie
[TABAC] chimie du tabac:tabac fumé:cigarette:cigarette électronique
[TABAC] étude
[TABAC] prévention:santé
[TABAC] sevrage tabagique
[TABAC] tabagisme:pathologie:pathologie bucco-dentaireIndex. décimale : TA 1.1.1 Cigarettes (« normales », électroniques, aromatisées,…) Résumé : Despite having been introduced over 10 years ago, there is little research into the effects of electronic cigarettes (e-cigs, electronic nicotine delivery systems, or ENDS) on health outcomes. These devices create an aerosol mixture by heating propylene glycol, glycerol, nicotine, additives and flavorings. Although concerns have been voiced about these devices, usage continues to increase, partially because they are marketed as a safer alternative to traditional cigarettes and as a smoking cessation aid. However, the chemicals in ENDS may deliver toxins to a variety of body systems, necessitating an urgent need for investigation into their biological effects. The oral cavity is the initial point of contact and the primary repository of nicotine deposition, which places the oral microbial environment at a high potential to be impacted by ENDS. Oral microbial homeostasis relies on an intricate balance between the host and their microbiome, but disruptions to this equilibrium can have wide-reaching effects. The purpose of this investigation was to examine the multi faceted impacts of ENDS on the different systems within the oral cavity, ranging from the microbiome to the human host, and the signaling molecules that connect these two. A tandem approach of in vitro and in vivo techniques was utilized to recapitulate the oral microenvironment and identify the mechanistic changes while also allowing for clinical correlations to be made. Systems were analyzed with a multi omics approach consisting of host transcriptomics, metatranscriptomics and metabolomics in combination with mass spectrometry and immunohistochemistry to identify potential biomarkers and risk for disease. Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10465 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : The impact of e-cigarettes on oral and dental health : narrative review Type de document : document électronique Auteurs : Mubarak Saeed Saad, Auteur ; Abdulhakeem Saeed Hamad, Auteur ; Mohammed Ali N Alasmari, Auteur Editeur : Scholars Middle East Publishers Année de publication : 2023 Collection : Saudi Journal of Medical and Pharmaceutical, ISSN 2413-4910 num. 9(12) Importance : p. 863-867 Langues : Anglais (eng) Catégories : [TABAC] chimie du tabac:constituant:alcaloïde:nicotine
[TABAC] chimie du tabac:tabac fumé:cigarette:cigarette électronique
[TABAC] tabagisme:pathologie:pathologie bucco-dentaire
[TABAC] tabagisme:risqueIndex. décimale : TA 3.2.2.6 Effets métaboliques et biologiques Résumé : E-cigarettes, also known as electronic cigarettes or vape pens, have become increasingly popular in recent years as an alternative to traditional tobacco products. However, there is growing concern about the potential impact of e-cigarettes on oral and dental health. This narrative review aims to provide an overview of the current evidence on the topic and to highlight the potential risks associated with e-cigarette use. One of the main concerns surrounding e-cigarettes is the potential for oral and dental health problems. E-cigarettes contain a liquid solution that is heated and inhaled as a vapor, and this vapor can contain a variety of chemicals and toxins. Some of these chemicals have been found to have adverse effects on oral health, including inflammation of the gums, dry mouth, and an increased risk of cavities. Additionally, the act of vaping itself can lead to oral health issues, as the repetitive motion of inhaling and exhaling can cause irritation to the mouth and throat. Furthermore, the nicotine content in e-cigarettes can also have negative effects on oral and dental health. Nicotine is a vasoconstrictor, meaning it restricts blood flow, which can lead to a decrease in the delivery of oxygen and nutrients to the gums and other oral tissues. This can result in a higher risk of gum disease and delayed healing after oral surgery or dental procedures. In addition, nicotine has been shown to contribute to the development of oral cancer, as well as other oral health issues such as tooth decay and tooth loss. More research is needed to fully understand the long-term effects of e-cigarettes on oral and dental health, but in the meantime, it is crucial for individuals to take steps to protect their oral health and to be aware of the potential risks associated with e-cigarette use. En ligne : https://doi.org/10.36348/sjmps.2023.v09i12.014 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10565 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : Toxic cultures: E-cigarettes and the oral microbial exposome Type de document : document électronique Auteurs : Purnima Kumar, Auteur ; Michelle Beverly, Auteur ; Sukirth Ganesan, Auteur Editeur : Springer Nature Année de publication : 2024 Collection : Biofilms and Microbiomes npj Importance : 24 p. Présentation : ill., graph. Langues : Anglais (eng) Catégories : [TABAC] chimie du tabac:tabac fumé:cigarette:cigarette électronique
[TABAC] étude
[TABAC] prévention:santé
[TABAC] tabagisme:effet du tabac
[TABAC] tabagisme:pathologie:pathologie bucco-dentaireIndex. décimale : TA 3.2.2.6 Effets métaboliques et biologiques Résumé : E-cigarettes have emerged as an exposomal factor of great concern to human health. We aimed to test the hypothesis that e-cigarette aerosol is metabolized in the oral cavity by the indigenous microbiome, leading to structural and functional alterations in oral biofilms. We combined untargeted metabolomic analysis of in vitro commensal-rich and pathogen-rich microcosm communities with metatranscriptomics, and fluorescent microscopy, and verified the results in human samples. Spectral deconvolution of 4,215 peaks identified 969 exposomal and endogenous metabolites that mapped to 23 metabolic pathways. Aerosol characteristics and biofilm composition affected metabolite profiles. Metabolites generated by commensal-rich biofilms contained antimitic, anti-fungal and anti-bacterial compounds, while pathogen-rich biofilms metabolized nicotine-containing aerosol using the pyridine and pyrrolidine pathways. Both communities generated endogenous metabolites that mapped to quorum sensing functions. Several of these metabolites were verified in the saliva of current, never, and former smokers who vape. Metatranscriptomics revealed upregulation of xenobiotic degradation, capsule, peptidoglycan, and glycosaminoglycan biosynthesis in commensal-rich communities, while genes encoding organic carbon-compound metabolism, antimicrobial resistance and secretion systems were over-expressed in pathogen-rich biofilms. Topographical analysis revealed an architecture characterized by low surface-area to biovolume ratio, high biomass, and diffusion distance only in commensal-rich biofilms. In conclusion, our data suggest that bacterial metabolism of e-cigarette aerosol triggers a quorum-sensing-regulated stress response which mediates the formation of dense, exopolysaccharide rich biofilms in health-compatible communities and antibiotic resistance and virulence amplification in disease-associated communities. These findings explain the higher incidence of dental caries, gingival inflammation, and antimicrobial resistance observed in vapers. En ligne : https://doi.org/10.21203/rs.3.rs-4629512/v1 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10479 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : Varied effects of tobacco smoke and e‑cigarette vapor suggest that nicotine does not affect endothelium‑dependent relaxation and nitric oxide signaling Type de document : document électronique Auteurs : Gerald Wölkart, Auteur ; Alexander Kollau, Auteur ; Michael Russwurm, Auteur ; Doris Koesling, Auteur ; Astrid Schrammel, Auteur ; Bernd Mayer, Auteur Editeur : Lisbonne [Portugal] : Observatoire europeen des drogues et des toxicomanies = European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) Année de publication : 2023 Collection : EMCDDA Scientific report Importance : 14 p. Présentation : tab., graph. Langues : Anglais (eng) Catégories : [TABAC] CANDIDATS:e-cigarette
[TABAC] chimie du tabac:constituant:alcaloïde:nicotine
[TABAC] tabagisme:pathologie:pathologie bucco-dentaire
[TABAC] tabagisme:tabagisme actif:fumeurMots-clés : test sur animal Index. décimale : TA 3.2.2.5 Pathologies cardiovasculaires Résumé : Chronic smoking causes dysfunction of vascular endothelial cells, evident as a reduction of flowmediated dilation in smokers, but the role of nicotine is still controversial. Given the increasing use of e-cigarettes and other nicotine products, it appears essential to clarify this issue. We studied extracts
from cigarette smoke (CSE) and vapor from e-cigarettes (EVE) and heated tobacco (HTE) for their effects on vascular relaxation, endothelial nitric oxide signaling, and the activity of soluble guanylyl cyclase. The average nicotine concentrations of CSE, EVE, and HTE were 164, 800, and 85 μM,
respectively. At a dilution of 1:3, CSE almost entirely inhibited the relaxation of rat aortas and porcine coronary arteries to acetylcholine and bradykinin, respectively, while undiluted EVE, with a 15-fold higher nicotine concentration, had no significant effect. With about 50% inhibition at 1:2 dilution,
the effect of HTE was between CSE and EVE. Neither extract affected endothelium-independent relaxation to an NO donor. At the dilutions tested, CSE was not toxic to cultured endothelial cells but, in contrast to EVE, impaired NO signaling and inhibited NO stimulation of soluble guanylyl cyclase. Our results demonstrate that nicotine does not mediate the impaired endothelium-dependent vascular relaxation caused by smoking.En ligne : https://doi.org/10.1038/s41598-023-42750-6 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10210 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
