Clinical study protocol on electronic cigarettes and nicotine pouches for smoking cessation in Pakistan / Abdul Hameed (2024)  

Public Titre : Clinical study protocol on electronic cigarettes and nicotine pouches for smoking cessation in Pakistan : a randomized controlled trial Type de document : document électronique Auteurs : Abdul Hameed, Auteur ; Daud Malik, Auteur Editeur : Springer Année de publication : 2024 Collection : Trials, ISSN 1745-6215 num. 25:9 Importance : 15 p. Présentation : ill, tab. Langues : Anglais (eng) Catégories : [DIVERS] géographie:Asie:Proche et Moyen-Orient:Pakistan [DIVERS] géographie:pays en développement [TABAC] CANDIDATS:e-cigarette [TABAC] étude:recherche:recherche clinique:essai clinique randomisé [TABAC] sevrage tabagique Mots-clés : pouche Index. décimale : TA 1.1.1 Cigarettes (« normales », électroniques, aromatisées,…) Résumé : Background Pakistan is one of most vulnerable low- and middle-income countries with 29 million adult active tobacco users. Smoking cessation services are lacking as the tobacco control initiatives have largely failed to address the smoking endemic. Over the last 5 years, Pakistan has witnessed the use of innovative tobacco harm reduction (THR) products such as e-cigarettes and nicotine pouches. However, their use remains limited. THR products are imported legally as consumer goods and are taxable. The lack of sufficient data for THR and its application is a challenge in gauging their effectiveness in assisting smokers quit combustible smoking. Evidence-based studies can help in measuring the effectiveness of e-cigarettes and nicotine pouches as smoking cessation aids. Method Keeping in view the study objectives, a sample size of 600 participants will be sufficient to assess the effectiveness of e-cigarettes and nicotine pouches for smoking cessation in Pakistan. Of these, 200 participants each will receive e-cigarettes and nicotine pouches along with basic care counselling, while the remaining 200 participants will only receive basic care counselling for 48 weeks. The association of participants’ characteristics with smoking and health status will be based on the bivariate and multivariate analysis. The simple t-test and variance analysis will assess the differences in intervention indicators between the control and treatment groups. For the inferential analysis, the average treatment impact will be based on the quasi-experimental techniques such as difference in difference (DID) or propensity score matching (PMS). Discussion The study will evaluate the participants at the baseline as they decide the quit date. After every 12 weeks, a follow-up survey with the participants will be conducted. Results are anticipated to inform the public, decisionmakers, and researchers about the effects of using e-cigarettes and nicotine pouches in the short- and medium-term periods. Critically, the potential of e-cigarettes and other alternative nicotine delivery systems as smoking cessation aid will be assessed. En ligne : https://doi.org/10.1186/s13063-023-07876-y Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10228

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Virtual reality cue exposure for the relapse prevention of tobacco consumption / Camille Giovancarli (2016)  

Public Titre : Virtual reality cue exposure for the relapse prevention of tobacco consumption : a study protocol for a randomized controlled trial Type de document : document électronique Auteurs : Camille Giovancarli, Auteur ; Eric Malbos, Auteur ; Karine Baumstarck, Auteur Editeur : Springer Année de publication : 2016 Collection : Trials, ISSN 1745-6215 num. 17 Importance : 9 p. Présentation : tab., ill. Langues : Anglais (eng) Catégories : [TABAC] étude [TABAC] sevrage tabagique [TABAC] sevrage tabagique:efficacité du sevrage:rechute [TABAC] sevrage tabagique:méthode de sevrage:méthode individuelle:approche psychologique:thérapie cognitivo-comportementale [TABAC] tabagisme:aspect psychologique:comportement Mots-clés : réalité virtuelle. Index. décimale : TA 6.5 Rechutes Résumé : Background: Successful interventions have been developed for smoking cessation, but the success of smoking relapse prevention interventions has been limited. In particular, cognitive behavioural therapy (CBT) has been hampered by a high relapse rate. Because relapses can be due to the presence of conditions associated with tobacco consumption (such as drinking in bars with friends), virtual reality exposure therapy (VRET) can generate synthetic environments that represent risk situations for the patient in the context of relapse prevention. The primary objective of this study is to evaluate the effectiveness of CBT coupled with VRET, in comparison to CBT alone, in the prevention of smoking relapse. The secondary objectives are to assess the impact of CBT coupled with VRET on anxiety, depression, quality of life, self-esteem and addictive comorbidities (such as alcohol, cannabis, and gambling). A third objective examines the feasibility and acceptability of VR use considering elements such as presence, cybersickness and number of patients who complete the VRET program. Method/design: The present study is a 14-month (2 months of therapy followed by 12 months of follow-up), prospective, comparative, randomized and open clinical trial, involving two parallel groups (CBT coupled with VRET versus CBT alone). The primary outcome is the proportion of individuals with tobacco abstinence at 6 months after the end of the therapy. Abstinence is defined by the total absence of tobacco consumption assessed during a post-test interview and with an apparatus that measures the carbon monoxide levels expired. A total of 60 individuals per group will be included. Discussion : This study is the first to examine the efficacy of CBT coupled with VRET in the prevention of smoking relapse. Because VRET is simple to use and has a low cost, this interactive therapeutic method might be easily implemented in clinical practice if the study confirms its efficacy En ligne : https://doi.org/10.1186/s13063-016-1224-5 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=9756

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