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Auteur Hayden McRobbie |
Documents disponibles écrits par cet auteur (5)


Titre : Electronic cigarettes for smoking cessation (Review) Type de document : document électronique Auteurs : Nicola Lindson, Auteur ; AR Butler, Auteur ; Hayden McRobbie, Auteur Editeur : The Cochrane Collaboration Année de publication : 2024 Collection : Cochrane Database of Systematic Reviews num. 1 Importance : 5 p. Langues : Anglais (eng) Catégories : [TABAC] chimie du tabac:constituant:alcaloïde:nicotine
[TABAC] chimie du tabac:tabac fumé:cigarette:cigarette électronique
[TABAC] sevrage tabagique
[TABAC] sevrage tabagique:méthode de sevrage:méthode individuelle:approche pharmacologique:effet secondaireIndex. décimale : TA 6.2.3.2 Autres produits Résumé : Background
Electronic cigarettes (ECs) are handheld electronic vaping devices which produce an aerosol by heating an e‐liquid. People who smoke, healthcare providers and regulators want to know if ECs can help people quit smoking, and if they are safe to use for this purpose. This is a review update conducted as part of a living systematic review.
Objectives
To examine the safety, tolerability and effectiveness of using electronic cigarettes (ECs) to help people who smoke tobacco achieve long‐term smoking abstinence, in comparison to non‐nicotine EC, other smoking cessation treatments and no treatment.
Search methods
We searched the Cochrane Tobacco Addiction Group's Specialized Register to 1 February 2023, and Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, Embase, and PsycINFO to 1 July 2023, and reference‐checked and contacted study authors.
Selection criteria
We included trials in which people who smoke were randomized to an EC or control condition. We also included uncontrolled intervention studies in which all participants received an EC intervention as these studies have the potential to provide further information on harms and longer‐term use. Studies had to report an eligible outcome.
Data collection and analysis
We followed standard Cochrane methods for screening and data extraction. Critical outcomes were abstinence from smoking after at least six months, adverse events (AEs), and serious adverse events (SAEs). We used a fixed‐effect Mantel‐Haenszel model to calculate risk ratios (RRs) with a 95% confidence interval (CI) for dichotomous outcomes. For continuous outcomes, we calculated mean differences. Where appropriate, we pooled data in pairwise and network meta‐analyses (NMA).
Main results
We included 88 completed studies (10 new to this update), representing 27,235 participants, of which 47 were randomized controlled trials (RCTs). Of the included studies, we rated ten (all but one contributing to our main comparisons) at low risk of bias overall, 58 at high risk overall (including all non‐randomized studies), and the remainder at unclear risk.
There is high certainty that nicotine EC increases quit rates compared to nicotine replacement therapy (NRT) (RR 1.59, 95% CI 1.29 to 1.93; I2 = 0%; 7 studies, 2544 participants). In absolute terms, this might translate to an additional four quitters per 100 (95% CI 2 to 6 more). There is moderate‐certainty evidence (limited by imprecision) that the rate of occurrence of AEs is similar between groups (RR 1.03, 95% CI 0.91 to 1.17; I2 = 0%; 5 studies, 2052 participants). SAEs were rare, and there is insufficient evidence to determine whether rates differ between groups due to very serious imprecision (RR 1.20, 95% CI 0.90 to 1.60; I2 = 32%; 6 studies, 2761 participants; low‐certainty evidence).
There is moderate‐certainty evidence, limited by imprecision, that nicotine EC increases quit rates compared to non‐nicotine EC (RR 1.46, 95% CI 1.09 to 1.96; I2 = 4%; 6 studies, 1613 participants). In absolute terms, this might lead to an additional three quitters per 100 (95% CI 1 to 7 more). There is moderate‐certainty evidence of no difference in the rate of AEs between these groups (RR 1.01, 95% CI 0.91 to 1.11; I2 = 0%; 5 studies, 1840 participants). There is insufficient evidence to determine whether rates of SAEs differ between groups, due to very serious imprecision (RR 1.00, 95% CI 0.56 to 1.79; I2 = 0%; 9 studies, 1412 participants; low‐certainty evidence).
Due to issues with risk of bias, there is low‐certainty evidence that, compared to behavioural support only/no support, quit rates may be higher for participants randomized to nicotine EC (RR 1.88, 95% CI 1.56 to 2.25; I2 = 0%; 9 studies, 5024 participants). In absolute terms, this represents an additional four quitters per 100 (95% CI 2 to 5 more). There was some evidence that (non‐serious) AEs may be more common in people randomized to nicotine EC (RR 1.22, 95% CI 1.12 to 1.32; I2 = 41%, low‐certainty evidence; 4 studies, 765 participants) and, again, insufficient evidence to determine whether rates of SAEs differed between groups (RR 0.89, 95% CI 0.59 to 1.34; I2 = 23%; 10 studies, 3263 participants; very low‐certainty evidence).
Results from the NMA were consistent with those from pairwise meta‐analyses for all critical outcomes, and there was no indication of inconsistency within the networks.
Data from non‐randomized studies were consistent with RCT data. The most commonly reported AEs were throat/mouth irritation, headache, cough, and nausea, which tended to dissipate with continued EC use. Very few studies reported data on other outcomes or comparisons, hence, evidence for these is limited, with CIs often encompassing both clinically significant harm and benefit.
Authors' conclusions
There is high‐certainty evidence that ECs with nicotine increase quit rates compared to NRT and moderate‐certainty evidence that they increase quit rates compared to ECs without nicotine. Evidence comparing nicotine EC with usual care/no treatment also suggests benefit, but is less certain due to risk of bias inherent in the study design. Confidence intervals were for the most part wide for data on AEs, SAEs and other safety markers, with no difference in AEs between nicotine and non‐nicotine ECs nor between nicotine ECs and NRT. Overall incidence of SAEs was low across all study arms. We did not detect evidence of serious harm from nicotine EC, but the longest follow‐up was two years and the number of studies was small.
The main limitation of the evidence base remains imprecision due to the small number of RCTs, often with low event rates. Further RCTs are underway. To ensure the review continues to provide up‐to‐date information to decision‐makers, this review is a living systematic review. We run searches monthly, with the review updated when relevant new evidence becomes available. Please refer to the Cochrane Database of Systematic Reviews for the review's current status.En ligne : https://doi.org/10.1002/14651858.CD010216.pub8 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10547 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Is a combination of varenicline and nicotine patch more effective in helping smokers quit than varenicline alone? / Peter Hajek (2013)
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Titre : Is a combination of varenicline and nicotine patch more effective in helping smokers quit than varenicline alone? : a randomised controlled trial Type de document : texte imprimé Auteurs : Peter Hajek, Auteur ; Katie Myers Smith, Auteur ; Al-Rehan Dhanji, Auteur ; Hayden McRobbie, Auteur Editeur : BioMed Central Année de publication : 2013 Collection : BMC Medicine, ISSN 1741-7015 Importance : p. 7 Langues : Français (fre) Catégories : [TABAC] étude:recherche:recherche clinique:essai clinique randomisé
[TABAC] sevrage tabagique:méthode de sevrage:méthode individuelle:approche pharmacologique:patch à la nicotine
[TABAC] sevrage tabagique:méthode de sevrage:méthode individuelle:approche pharmacologique:substitution nicotinique
[TABAC] sevrage tabagique:méthode de sevrage:méthode individuelle:approche pharmacologique:varéniclineIndex. décimale : TA 6.2.3 Approche pharmacologique Résumé : Background
Nicotine replacement therapy (NRT) and varenicline are both effective in helping smokers quit. There is growing interest in combining the two treatments to improve treatment outcomes, but no experimental data exist on whether this is efficacious. This double-blind randomised controlled trial was designed to evaluate whether adding nicotine patches to varenicline improves withdrawal relief and short-term abstinence rates.
Methods
117 participants seeking help to stop smoking were randomly allocated to varenicline plus placebo patch or varenicline plus nicotine patch (15 mg/16 hour). Varenicline use commenced one week prior to the target quit date (TQD), patch use started on the TQD. Ratings of urges to smoke and cigarette withdrawal symptoms were collected weekly over 4 weeks post-TQD. Medication use and smoking status were established at 1, 4 and 12 weeks. Participants lost to follow-up were included as continuing smokers.
Results
92% of participants used both medications during the first week after the TQD. The combination treatment generated no increase in nausea or other adverse effects. It had no overall effect on urges to smoke or on other withdrawal symptoms. The combination treatment did not improve biochemically validated abstinence rates at 1 week and 4 weeks post-TQD (69% vs 59%, p=0.28 and 60% vs 59%, p=0.91, in the nicotine patch and placebo patch arm, respectively), or self reported abstinence rates at 12 weeks (36% vs. 29%, p=0.39, NS).
Conclusions
The efficacy of varenicline was not enhanced by the addition of nicotine patches, although further trials would be useful to exclude the possibility of type II error.En ligne : https://bmcmedicine.biomedcentral.com/articles/10.1186/1741-7015-11-140 Format de la ressource électronique : HTML, PDF Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=7445 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : Manual of smoking cessation : a guide for councellors and practitioners Type de document : texte imprimé Auteurs : Andy Mcewen, Auteur ; Peter Hajek, Auteur ; Hayden McRobbie, Auteur ; Robert West, Auteur Editeur : Blackwell Publishing Année de publication : 2007 Importance : 151 p. ISBN/ISSN/EAN : 978-1-4051-3337-1 Langues : Anglais (eng) Catégories : [TABAC] étude:statistique
[TABAC] prévention:méthodologie
[TABAC] sevrage tabagique
[TABAC] sevrage tabagique:aide au sevrage:conseil de sevrageIndex. décimale : TA 6.1 Généralités Résumé : Ce Manuel de désaccoutumance au tabac donne les connaissances indispensables requises si vous êtes impliqués dans l'aide à l'arrêt des fumeurs. Le manuel fournit des faits, des chiffres, des interventions suggérées et des sources d'information pour aller plus loin dans les traitements empiriques avec les fumeurs désireux d'arrêter. Ce manuel couvre les principaux domaines et résultats d'apprentissage comme décrits dans les normes pour la formation à la désaccoutumance du tabac (Standard for Training in Smoking Cessation, Health Development Agency, 2003). Le manuel est divisé en deux parties : la première fournit les informations essentielles sur les données démographiques du tabagisme, avec les risques liés au tabagisme et les bénéfices à l'arrêt la deuxième offre un éventail de conseils pratiques à mettre en œuvre avec les patients. Le Manuel de désaccoutumance au tabac est un texte essentiel pour tous ceux qui sont impliqués dans les interventions en cessation du tabagisme, y compris les conseillers en abandon du tabagisme, les infirmières, les pharmaciens, médecins, officiers de la promotion de la santé, les professionnels dentaires et d'autres membres des équipes de soins de santé. Le livre est une ressource inestimable pour l'apprentissage sur la cessation du tabagisme, et un bref aide-mémoire à ceux pratiquant déjà dans le domaine. Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=1824 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité TA 002226 TA 6.1 MCE M Monographie Bibliothèque FARES Tabac Disponible Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Mobile phone text messaging and app-based interventions for smoking cessation (Review) / Robyn Whittaker (2019)
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Titre : Mobile phone text messaging and app-based interventions for smoking cessation (Review) Type de document : texte imprimé Auteurs : Robyn Whittaker, Auteur ; Hayden McRobbie, Auteur ; Christopher Bullen, Auteur Editeur : The Cochrane Collaboration Année de publication : 2019 Collection : Cochrane Database of Systematic Reviews num. 10 Importance : 85 p. Langues : Anglais (eng) Catégories : [TABAC] étude
[TABAC] étude:statistique
[TABAC] sevrage tabagique:méthode de sevrage:méthode individuelle:application mobileIndex. décimale : TA 6.2.5 Autres méthodes de sevrage Résumé : Les programmes utilisables à l'aide d'un téléphone mobile peuvent‐ils aider à arrêter de fumer ?
Contexte
Le tabagisme est l'une des principales causes de mortalité évitable. Les téléphones portables peuvent être utilisés pour aider les personnes voulant arrêter de fumer. Dans cette revue, nous nous sommes concentrés sur les programmes utilisant des messages (textos) ou des applications pour smartphones pour le faire.
Date de recherche
Nous avons recherché des études publiées et non publiées en octobre 2018.
Caractéristiques des études
Nous avons inclus 26 études contrôlées randomisées (impliquant plus de 33 000 personnes) ayant comparé les taux d’arrêt du tabac chez les personnes ayant reçu des messages ou des applications pour smartphone, pour les aider à arrêter de fumer, avec d’autres n’ayant pas bénéficié de ces programmes. Nous étions intéressés par des études évaluant le tabagisme pendant six mois ou plus.
Principaux résultats
Nous avons constaté que les programmes de messagerie pouvaient être efficaces dans le soutien des gens arrêtant de fumer, et augmenter les taux d’arrêt de 50 à 60 %. C'était le cas lorsqu'on les comparait à un soutien minimal ou lorsqu'on les testait comme un complément d'autres formes de soutien pour arrêter de fumer. Il n'y avait pas assez de preuves pour déterminer l'effet des applications pour smartphones.
Qualité et exhaustivité des preuves
La plupart des études étaient de grande qualité, bien que trois d'entre elles présentaient des taux d'abandon élevés. Nous avons une confiance modérée dans les résultats des interventions par messages, mais il y avait quelques problèmes à cause de différences inexpliquées entre les résultats des études et, pour certaines comparaisons, peu de données étaient disponibles. Nous avons peu confiance en les résultats concernant les applications pour smartphones, et d'autres études sont nécessaires dans ce domaine.En ligne : https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD006611.pub5/full/fr Format de la ressource électronique : HTML, PDF Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=9098 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : A multimedia mobile-phone-based youth smoking cessation intervention : findings from content development and piloting studies Type de document : texte imprimé Auteurs : Robyn Whittaker, Auteur ; Ralph Maddison, Auteur ; Hayden McRobbie, Auteur ; Christopher Bullen, Auteur Editeur : Toronto [Canada] : JMIR Publications Année de publication : 2008 Collection : Journal of medical internet research, ISSN 1438-8871 Importance : 11 p. Langues : Anglais (eng) Catégories : [DIVERS] personne:par âge:jeune
[TABAC] sevrage tabagique:aide au sevrage:accompagnement
[TABAC] sevrage tabagique:méthode de sevrage:méthode individuelle:application mobileIndex. décimale : TA 6.2 Méthodes individuelles Résumé : Background
While most young people who smoke want to quit, few access cessation support services. Mobile phone–based cessation programs are ideal for young people: mobile phones are the most common means of peer communication, and messages can be delivered in an anonymous manner, anywhere, anytime. Following the success of our text messaging smoking cessation program, we developed an innovative multimedia mobile phone smoking cessation intervention.
Objective
The aim of the study was to develop and pilot test a youth-oriented multimedia smoking cessation intervention delivered solely by mobile phone.
Methods
Development included creating content and building the technology platform. Content development was overseen by an expert group who advised on youth development principles, observational learning (from social cognitive theory), effective smoking cessation interventions, and social marketing. Young people participated in three content development phases (consultation via focus groups and an online survey, content pre-testing, and selection of role models). Video and text messages were then developed, incorporating the findings from this research. Information technology systems were established to support the delivery of the multimedia messages by mobile phone. A pilot study using an abbreviated 4-week program of video and text content tested the reliability of the systems and the acceptability of the intervention.
Results
Approximately 180 young people participated in the consultation phase. There was a high priority placed on music for relaxation (75%) and an interest in interacting with others in the program (40% would read messages, 36% would read a blog). Findings from the pre-testing phase (n = 41) included the importance of selecting “real” and “honest” role models with believable stories, and an interest in animations (37%). Of the 15 participants who took part in the pilot study, 13 (87%) were available for follow-up interviews at 4 weeks: 12 participants liked the program or liked it most of the time and found the role model to be believable; 7 liked the role model video messages (5 were unsure); 8 used the extra assistance for cravings; and 9 were happy with two messages per day. Nine participants (60%) stopped smoking during the program. Some technical challenges were encountered during the pilot study.
Conclusions
A multimedia mobile phone smoking cessation program is technically feasible, and the content developed is appropriate for this medium and is acceptable to our target population. These results have informed the design of a 6-month intervention currently being evaluated for its effectiveness in increasing smoking cessation rates in young people.En ligne : https://www.jmir.org/2008/5/e49/ Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=8054 Aucun avis, veuillez vous identifier pour ajouter le vôtre !