Acrolein yields in mainstream smoke from commercial cigarette and little cigar tobacco products / Todd, L. Cecil (2017)

Public Titre : Acrolein yields in mainstream smoke from commercial cigarette and little cigar tobacco products Type de document : document électronique Auteurs : Todd, L. Cecil, Auteur ; Tim, M. Brewer, Auteur ; Mimy Young, Auteur Editeur : Oxford University Press Année de publication : 2017 Collection : Nicotine and Tobacco Research Importance : p. 865-870 Présentation : tab.,graph. Langues : Anglais (eng) Catégories : [TABAC] chimie du tabac:fumée:acroléine [TABAC] chimie du tabac:tabac fumé:cigarette:cigarette filtre [TABAC] étude Index. décimale : TA 1.1.1 Cigarettes (« normales », électroniques, aromatisées,…) Résumé : Introduction: Many carbonyls are produced from the combustion of tobacco products and many of these carbonyls are harmful or potentially harmful constituents of mainstream cigarette smoke. One carbonyl of particular interest is acrolein, which is formed from the incomplete combustion of organic matter and the most significant contributor to non-cancer respiratory effects from cigarette smoke. Sheet-wrapped cigars, also known as “little cigars,” are a type of tobacco products that have not been extensively investigated in literature. Methods: This study uses standard cigarette testing protocols to determine the acrolein yields from sheet-wrapped cigars. Sheet-wrapped cigar and cigarette products were tested by derivatizing the mainstream smoke with 2,4-dinitrophenylhydrazine (DNPH) solution and then quantifying the derivatives using conventional analytical systems. Results: The results demonstrate that sheet-wrapped cigars can be tested for acrolein yields in mainstream smoke using the same methods used for the evaluation of cigarettes. The variability in the sheet-wrapped cigars and cigarettes under the International Organization for Standardization smoking regimen is statistically similar at the 95% confidence interval; however, increased variability is observed for sheet-wrapped cigar products under the Health Canada Intense (CI) smoking regimen. Conclusion: The amount of acrolein released by smoking sheet-wrapped cigars can be measured using standard smoking regimen currently used for cigarettes. The sheet-wrapped cigars were determined to yield similar quantity of acrolein from commercial cigarette products using two standard smoking regimens. Implications: This article reports on the measured quantity of acrolein from 15 commercial sheetwrapped cigars using a validated standard smoking test method that derivatizes acrolein in the mainstream smoke with DNPH solution, and uses Liquid Chromatography/Ultra-Violet Detection (LC/UV) for separation and detection. These acrolein yields were similar to the levels found in the smoke from 35 commercial cigarette products measured in the same manner. Although sheetwrapped cigar data were slightly more variable than those found for the cigarette data, this article reports that the production of acrolein is similar to cigarettes. The results demonstrate that sheet-wrapped cigars can be tested for acrolein yields in mainstream smoke using the same methods used for the evaluation of cigarettes. Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=9705

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Carcinogenic and non‑carcinogenic health risk assessment of organic compounds and heavy metals in electronic cigarettes / Siyuan Zhao (2023)  

Public Titre : Carcinogenic and non‑carcinogenic health risk assessment of organic compounds and heavy metals in electronic cigarettes Type de document : document électronique Auteurs : Siyuan Zhao, Auteur ; Xi Zhang, Auteur ; Junji Wang, Auteur ; Jianzai Lin, Auteur Editeur : Springer Nature Année de publication : 2023 Collection : Scientific Reports Importance : 13 p. Présentation : tab. Langues : Anglais (eng) Catégories : [TABAC] CANDIDATS:e-cigarette [TABAC] chimie du tabac:fumée:acétone [TABAC] chimie du tabac:fumée:acroléine [TABAC] chimie du tabac:tabac fumé:cigarette:cigarette électronique [TABAC] étude [TABAC] tabagisme:risque Index. décimale : TA 1.1.1 Cigarettes (« normales », électroniques, aromatisées,…) Résumé : E-cigarettes are now very popular in the world. Compared to traditional cigarettes, e-cigarettes are often considered safer and healthier. However, their safety remains controversial and requires further research and regulation. In this study, we aimed to understand the possible hazards to humans of four compounds (formaldehyde, acetaldehyde, acrolein, and acetone) and seven heavy metals (arsenic, cadmium, manganese, lead, copper, nickel, and chromium) contained in e-cigarette liquids and aerosols and perform a health risk assessment. We searched PubMed, CNKI, and other databases for relevant literature to obtain data on organic compounds and heavy metals in e-cigarette liquids and aerosols, and conducted acute, chronic, and carcinogenic risk assessments of various chemicals by different exposure routes. This study showed that exposure to four organic compounds and seven heavy metals in e-cigarette aerosols and e-liquids can cause varying levels of health risks in humans through different routes, with the inhalation route posing a higher overall risk than dermal exposure and oral intake. Various chemicals at high exposure doses can produce health risks beyond the acceptable range. E-cigarette designers must improve their products by changing the composition of the e-liquid and controlling the power of the device to reduce the health effects on humans. En ligne : https://doi.org/10.1038/s41598-023-43112-y Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10256

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