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Titre : Association between spending on social protection and tuberculosis burden : a global analysis Type de document : document électronique Auteurs : Andrew Siroka, Auteur ; Ninez A. Ponce, Auteur ; Knut Lönnroth, Auteur Editeur : Lancet Année de publication : 2015 Collection : The Lancet Infectious diseases, ISSN 1473-3099 num. 16(4) Importance : p.473-479 Langues : Anglais (eng) Catégories : [TUBER] aspect socio-économique
[TUBER] surveillanceIndex. décimale : TU 3. Stratégies et programmes de prévention et de contrôle Résumé : The End TB Strategy places great emphasis on increasing social protection and poverty alleviation programmes. However, the role of social protection on controlling tuberculosis has not been examined fully. We analysed the association between social protection spending and tuberculosis prevalence, incidence, and mortality globally. En ligne : https://doi.org/10.1016/S1473-3099(15)00401-6 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10028 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Population-based resistance of Mycobacterium tuberculosis isolates to pyrazinamide and fluoroquinolones / Matteo Zignol (2016)
Titre : Population-based resistance of Mycobacterium tuberculosis isolates to pyrazinamide and fluoroquinolones : results from a multicountry surveillance project Type de document : document électronique Auteurs : Matteo Zignol, Auteur ; Anna Dean, Auteur ; Natavan Alikhanova, Auteur Editeur : Lancet Année de publication : 2016 Collection : The Lancet Infectious diseases, ISSN 1473-3099 num. 16(10) Importance : p. 1185–1192 Langues : Anglais (eng) Catégories : [DIVERS] géographie:Afrique:Afrique subsaharienne:Afrique du Sud
[DIVERS] géographie:Europe:Europe centrale et orientale
[TUBER] traitement:résistance
[TUBER] traitement:traitement curatif
[PROMOSAN] étude:enquêteIndex. décimale : TU 8.2. Traitement curatif Résumé : Background
Pyrazinamide and fluoroquinolones are essential antituberculosis drugs in new rifampicin-sparing regimens. However, little information about the extent of resistance to these drugs at the population level is available.
Methods
In a molecular epidemiology analysis, we used population-based surveys from Azerbaijan, Bangladesh, Belarus, Pakistan, and South Africa to investigate resistance to pyrazinamide and fluoroquinolones among patients with tuberculosis. Resistance to pyrazinamide was assessed by gene sequencing with the detection of resistance-conferring mutations in the pncA gene, and susceptibility testing to fluoroquinolones was conducted using the MGIT system.
Findings
Pyrazinamide resistance was assessed in 4972 patients. Levels of resistance varied substantially in the surveyed settings (3·0–42·1%). In all settings, pyrazinamide resistance was significantly associated with rifampicin resistance. Among 5015 patients who underwent susceptibility testing to fluoroquinolones, proportions of resistance ranged from 1·0–16·6% for ofloxacin, to 0·5–12·4% for levofloxacin, and 0·9–14·6% for moxifloxacin when tested at 0·5 μg/mL. High levels of ofloxacin resistance were detected in Pakistan. Resistance to moxifloxacin and gatifloxacin
when tested at 2 μg/mL was low in all countries.
Interpretation
Although pyrazinamide resistance was significantly associated with rifampicin resistance, this drug may still be effective in 19–63% of patients with rifampicin-resistant tuberculosis. Even though the high level of resistance to ofloxacin found in Pakistan is worrisome because it might be the expression of extensive and unregulated use of fluoroquinolones in some parts of Asia, the negligible levels of resistance to fourth-generation fluoroquinolones documented in all survey sites is an encouraging finding. Rational use of this class of antibiotics should therefore be ensured to preserve its effectiveness.En ligne : https://doi.org/10.1016/S1473-3099(16)30190-6 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10783 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : Prevalence of and risk factors for active tuberculosis in migrants screened before entry to the UK : a population-based cross-sectional study Type de document : document électronique Auteurs : Robert W. Aldridge, Auteur ; Dominik Zenner, Auteur ; Peter J. White, Auteur Editeur : Lancet Année de publication : 2016 Collection : The Lancet Infectious diseases, ISSN 1473-3099 num. vol. 16 nr 8 Importance : p.962-970 Langues : Anglais (eng) Catégories : [DIVERS] géographie:Europe:Europe occidentale:Royaume-Uni
[DIVERS] personne:migrant
[TUBER] diagnostic
[TUBER] étude:statistique:prévalence
[TUBER] type de tuberculose:tuberculose-maladieIndex. décimale : TU 3.6.b. Réfugiés / migrants En ligne : https://doi.org/10.1016/S1473-3099(16)00072-4 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10157 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Accompagne Prevalence of and risk factors for active tuberculosis in migrants screened before entry to the UK / Robert W. Aldridge (2016)
Titre : Tackling tuberculosis in migrants Type de document : document électronique Auteurs : Marieke van der Werf, Auteur ; Piotr Kramarz, Auteur Editeur : Lancet Année de publication : 2016 Collection : The Lancet Infectious diseases, ISSN 1473-3099 num. vol. 16 nr 8 Importance : p.877-878 Présentation : ill. Langues : Anglais (eng) Catégories : [TUBER] traitement
[TUBER] type de tuberculose:tuberculose-maladie
[DIVERS] personne:migrantIndex. décimale : TU 3.6.b. Réfugiés / migrants Résumé : Commentaire sur un article En ligne : http://dx.doi.org/10.1016/ S1473-3099(16)00148-1 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10156 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
fait partie de Association between spending on social protection and tuberculosis burden / Andrew Siroka (2015)
Titre : The impact of social protection on tuberculosis rates : a global analysis Type de document : document électronique Auteurs : Andrew Siroka, Auteur ; Knut Lönnroth, Auteur ; Ninez A. Ponce, Auteur Editeur : Lancet Année de publication : 2016 Collection : The Lancet Infectious diseases, ISSN 1473-3099 num. vol.16 nr 4 Importance : p. 473–479 Présentation : ill. ; tab. ; graph. Langues : Anglais (eng) Catégories : [DIVERS] association:association internationale:Organisation Mondiale de la Santé
[TUBER] aspect socio-économique
[TUBER] étude:épidémiologie:groupe à risque:précaritéIndex. décimale : TU 4.4.f. Milieu précarisé (sans abris, drogués,...) Résumé : Background
The End TB Strategy places great emphasis on increasing social protection and poverty alleviation programmes. However, the role of social protection on controlling tuberculosis has not been examined fully. We analysed the association between social protection spending and tuberculosis prevalence, incidence, and mortality globally.
Methods
We used publicly available data from WHO's Global Tuberculosis Programme for tuberculosis burden in terms of yearly incidence, prevalence, and mortality per 100 000 people, and social protection data from the International Labour Organization (ILO), expressed as the percentage of national gross domestic product (GDP) spent on social protection programmes (excluding health). Data from ILO were from 146 countries covering the years between 2000 and 2012. We used descriptive assessments to examine levels of social protection and tuberculosis burden for each country, then used these assessments to inform our fully adjusted multivariate regression models. Our models controlled for economic output, adult HIV prevalence, health expenditure, population density, the percentage of foreign-born residents, and the strength of the national tuberculosis treatment programme, and also incorporated a country-level fixed effect to adjust for clustering of datapoints within countries.
Findings
Overall, social protection spending levels were inversely associated with tuberculosis prevalence, incidence, and mortality. For a country spending 0% of their GDP on social protection, moving to spending 1% of their GDP was associated with a change of −18·33 per 100 000 people (95% CI −32·10 to −4·60; p=0·009) in prevalence, −8·16 per 100 000 people (−16·00 to −0·27; p=0·043) in incidence, and −5·48 per 100 000 people (−9·34 to −1·62; p=0·006) in mortality. This association was mitigated at higher levels of social protection spending, and lost significance when more than 11% of GDP was spent.
Interpretation
Our findings suggest that investments in social protection could contribute to a reduced tuberculosis burden, especially in countries that are investing a small proportion of their GDP in this area. However, further research is needed to support these ecological associations.En ligne : https://doi.org/10.1016/S1473-3099(15)00401-6 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10152 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : The transmission of Mycobacterium tuberculosis in high burden settings Type de document : document électronique Auteurs : Tom A. Yates, Auteur Editeur : Lancet Année de publication : 2016 Collection : The Lancet Infectious diseases, ISSN 1473-3099 num. 16 Importance : p.227-238 Langues : Anglais (eng) Catégories : [TUBER] cause:contagion Index. décimale : TU 3.6. Groupes à risques En ligne : https://doi.org/10.1016/S1473-3099(15)00499-5 Format de la ressource électronique : HTML, PDF Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=9426 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
