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Titre : Active smoking compromises IVF outcome and affects ovarian reserve Type de document : document électronique Auteurs : Thomas Freour, Auteur ; Damien Masson, Auteur ; Sophie Mirallie, Auteur ; Kalyane Bach, Auteur ; Miguel Jean, Auteur ; Thomas Dejoie, Auteur ; Paul Barriere, Auteur Editeur : Elsevier Science Direct Année de publication : 2008 Collection : Reproductive BioMedicine Online, ISSN 1472-6491 num. vol.16 n°1 Importance : p.96-102 Langues : Français (fre) Catégories : [TABAC] tabagisme:effet du tabac:altération de la fonction sexuelle:effet sur la fertilité
[TABAC] tabagisme:risque:facteur associé:grossesseIndex. décimale : TA 3.2.2.7 Grossesse et fœtus Résumé : Although the association between smoking and female infertility is now largely demonstrated, the proportion of smokers in women of reproductive age remains important. Tobacco contains numerous toxicants that could affect ovarian reserve and lead to poor prognosis in assisted reproductive techniques. To investigate the effect of female active smoking on ovarian reserve and IVF outcome, smoking status, hormonal status, i.e. serum FSH, oestradiol and anti-Müllerian hormone (AMH), ovarian response to hyperstimulation, i.e. mature oocytes retrieved, and IVF outcome, i.e. clinical pregnancy, were retrospectively analysed in 111 women undergoing IVF-embryo transfer cycles. Compared with non-smokers (n = 71), active smoking women (n = 40) had decreased ovarian response (12.12 ± 5 versus 8.62 ± 4 mature oocytes retrieved) to hyperstimulation and lower clinical pregnancy rate (29.6 versus 10.0%). Serum AMH concentrations were lower in the smoker group (3.86 ± 1.92 versus 3.06 ± 1.68 μg/l) and had no predictive value for ovarian response, inversely to non-smokers. In conclusion, active smoking is associated with poor prognosis in assisted reproduction cycles, i.e. ovarian response and pregnancy, and leads to altered ovarian reserve, as reflected by decreased serum AMH concentrations. En ligne : https://doi.org/10.1016/S1472-6483(10)60561-5 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10104 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : An in vitro toxicological assessment of two electronic cigarettes : e-liquid to aerosolisation Type de document : document électronique Auteurs : Emma Bishop, Auteur ; Fabio Miazzi, Auteur ; S. Bozhilova, Auteur Editeur : Elsevier Science Direct Année de publication : 2024 Collection : Current Research in Toxicology num. 6 Importance : 36 p. Présentation : ill., tab., graph. Langues : Anglais (eng) Catégories : [TABAC] CANDIDATS:e-cigarette
[TABAC] chimie du tabac:constituant:additif:agent de saveur
[TABAC] chimie du tabac:tabac fumé:cigarette:cigarette électronique
[TABAC] étude
[TABAC] tabagisme:tabagisme passifMots-clés : arôme - e-liquide - mécanisme de l'appareil- vapotage hors tabagisme passif - toxicologie - aérosol - test dans le sens de tester les produits, l'appareil Index. décimale : TA 1.1.1 Cigarettes (« normales », électroniques, aromatisées,…) Résumé : Interest in the toxicological assessment of iterations of e-cigarette devices, e-liquid formulations and flavour use is increasing. Here, we describe a multiple test matrix and
in vitro approach to assess the biological impact of differing e-cigarette activation mechanism (button vs puff-activated) and heating technology (cotton vs ceramic wick). The e-liquids selected for each device contained the same nicotine concentration and flavourings. We tested both e-liquid and aqueous extract of e-liquid aerosol using a high throughput
cytotoxicity and genotoxicity screen. We also conducted whole aerosol assessment both in a reconstituted human airway lung tissue (MucilAir) with associated endpoint assessment
(cytotoxicity, TEER, cilia beat frequency and active area) and an Ames whole aerosol assay with up to 900 consecutive undiluted puffs. Following this testing it is shown that the
biological impact of these devices is similar, taking into consideration the limitations and capturing efficiencies of the different testing matrices. We have contextualised these
responses against previous published reference cigarette data to establish the comparative reduction in response consistent with reduced risk potential of the e-cigarette products
tested in this study as compared to conventional cigarettes.Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10187 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Classification of patterns of tobacco and cannabis co-use based on temporal proximity / Nhung Nguyen (2024)
Titre : Classification of patterns of tobacco and cannabis co-use based on temporal proximity : a qualitative study among young adults Type de document : document électronique Auteurs : Nhung Nguyen, Auteur ; Sabrina Islam, Auteur ; Karla D. Llanes, Auteur ; Kimberly A. Koester, Auteur ; Pamela M. Ling, Auteur Editeur : Elsevier Science Direct Année de publication : 2024 Collection : Addictive Behaviors num. 152 Importance : 8 p. Présentation : ill., tab. Langues : Anglais (eng) Catégories : [DIVERS] personne:par âge:jeune
[TABAC] étude
[TABAC] tabagisme:risque:facteur associé:drogue:cannabisIndex. décimale : TA 1.1.5 Cannabis Résumé : Purpose:
Co-use of tobacco and cannabis is a common and complex behavior. The lack of harmonized measures of co-use yields confusion and inconsistencies in synthesizing evidence about the health effects of co-use. We aimed to classify co-use patterns based on temporal proximity and describe preferred products and motives for each
pattern in order to improve co-use surveillance.
Methods: We conducted semi-structured interviews in a sample of 34 young adults (Mage = 22.8 years, 32.4 % female) during 2017–2019 in California, USA. We employed a qualitative thematic analysis to identify timing, reasons, and contexts for tobacco and cannabis co-use and classify co-use patterns.
Results:
Four emergent patterns of co-use with increasing temporal proximity between tobacco use and cannabis use were: Same-month different-day co-use (Pattern 1); Same-day different-occasion co-use (Pattern 2); Same-occasion sequential co-use (Pattern 3); and Same-occasion simultaneous co-use (Pattern 4). Participants used various product combinations within each pattern. Similar motives for all patterns were socialization, product availability, and coping with stress/anxiety. Unique motive for temporally distant patterns (Patterns 1 and 2) was seeking substancespecific effects (e.g., stimulant effect from nicotine, relaxation effects from cannabis), while unique motives for temporally close patterns (Patterns 3 and 4) were seeking combined effects from both substances (e.g., more intense psychoactive effects, mitigating cannabis adverse effects) and behavioral trigger (e.g., cannabis use triggers tobacco use).
Conclusions:
Our classification of co-use patterns can facilitate consistency for measuring co-use and assessing its health impacts. Future research should also measure product types and motives for different patterns to inform intervention efforts.Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10207 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Comparative systematic review on the safety of e-cigarettes and conventional cigarettes / Josef Yayan (2024)
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Titre : Comparative systematic review on the safety of e-cigarettes and conventional cigarettes Type de document : document électronique Auteurs : Josef Yayan, Auteur ; Karl-Josef Franke, Auteur ; Christian Biancosino, Auteur ; Kurt Rasche, Auteur Editeur : Elsevier Science Direct Année de publication : 2024 Collection : Food and chemical toxicology, ISSN 1873-6351 num. 185 Importance : p. 1-6 Présentation : ill. Langues : Anglais (eng) Catégories : [TABAC] chimie du tabac:substance toxique
[TABAC] chimie du tabac:tabac fumé:cigarette
[TABAC] chimie du tabac:tabac fumé:cigarette:cigarette électronique
[TABAC] étude:méta-analyse
[TABAC] tabagisme:risqueIndex. décimale : TA 1.1.1 Cigarettes (« normales », électroniques, aromatisées,…) Résumé : Background
This systematic review evaluated the health risks of electronic cigarettes (e-cigarettes) compared to traditional cigarettes. It examines various studies and research on the subject to provide a comprehensive analysis of potential health risks associated with both smoking methods.
Methods
The systematic review, incorporating searches in PubMed, Scopus, Web of Science, and the Cochrane Library up to July 2023, examines the results obtained in relevant studies, and provides a critical discussion of the results.
Results
E-cigarettes exhibit reduced exposure to harmful toxins compared to traditional cigarettes.
Conclusion
However, concerns persist regarding respiratory irritation and potential health risks, especially among youth, emphasizing the need for comprehensive, long-term research and protective legislation.En ligne : https://doi.org/10.1016/j.fct.2024.114507 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10539 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Comparison of cellulose vs. plastic cigarette filter decomposition under distinct disposal environments / François-Xavier Joly (2017)
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Titre : Comparison of cellulose vs. plastic cigarette filter decomposition under distinct disposal environments Type de document : document électronique Auteurs : François-Xavier Joly, Auteur ; Mathieu Coulis, Auteur Editeur : Elsevier Science Direct Année de publication : 2017 Collection : Waste Management, ISSN 1879-2456 num. 72 Importance : p.349-353 Présentation : tab., graph. Langues : Anglais (eng) Catégories : [TABAC] chimie du tabac:tabac fumé:cigarette:cigarette filtre
[TABAC] tabagisme:effet sur l'environnement:mégot
[TABAC] tabagisme:effet sur l'environnement:pollutionIndex. décimale : TA 1.1.1 Cigarettes (« normales », électroniques, aromatisées,…) Résumé : It is estimated that 4.5 trillion cigarette butts are discarded annually, making them numerically the most common type of litter on Earth. To accelerate their disappearance after disposal, a new type of cigarette filters made of cellulose, a readily biodegradable compound, has been introduced in the market. Yet, the
advantage of these cellulose filters over the conventional plastic ones (cellulose acetate) for decomposition, remains unknown. Here, we compared the decomposition of cellulose and plastic cigarettes filters, either intact or smoked, on the soil surface or within a composting bin over a six-month field decomposition experiment. Within the compost, cellulose filters decomposed faster than plastic filters, but this advantage was strongly reduced when filters had been used for smoking. This indicates that the accumulation of tars and other chemicals during filter use can strongly affect its subsequent decomposition.
Strikingly, on the soil surface, we observed no difference in mass loss between cellulose and plastic filters throughout the incubation. Using a first order kinetic model for mass loss of for used filters over the short period of our experiment, we estimated that conventional plastic filters take 7.5–14 years to disappear, in the compost and on the soil surface, respectively. In contrast, we estimated that cellulose filters take 2.3– 13 years to disappear, in the compost and on the soil surface, respectively. Our data clearly showed that disposal environments and the use of cellulose filters must be considered when assessing their advantage over plastic filters. In light of our results, we advocate that the shift to cellulose filters should not exempt users from disposing their waste in appropriate collection systems.
En ligne : https://doi.org/10.1016/j.wasman.2017.11.023 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=9804 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : Content analysis of IQOS direct mail and email marketing in the US Type de document : document électronique Auteurs : Katherine C. Henderson, Auteur ; Nikita G. Kute, Auteur ; Lucy Popova, Auteur Editeur : Elsevier Science Direct Année de publication : 2024 Collection : Preventive Medicine Reports, ISSN 2211-3355 num. 38 Importance : 5 p. Présentation : ill. Langues : Anglais (eng) Catégories : [DIVERS] géographie:Amérique:Amérique du Nord:Etats-Unis
[TABAC] chimie du tabac:tabac non fumé:tabac chauffé
[TABAC] économie du tabac:marketing
[TABAC] étudeIndex. décimale : TA 8.9 Techniques de l'industrie du tabac Résumé : Objective
Novel nicotine and tobacco products, including heated tobacco products (HTPs) like IQOS, are growing in global popularity. IQOS was the first HTP authorized for sale by the US Food and Drug Administration, entering the US market in 2019 and being removed in 2021 due to patent-related legal challenges, with the possibility of returning in 2024. Direct marketing is one method tobacco companies use to reach consumers of these products. The purpose of this study was to investigate the content of US IQOS direct mail and email marketing.
Methods
Direct marketing items were collected between September 2019 and July 2021 by seven team members in the first US IQOS test market, Atlanta, Georgia.
Results
Overall, 101 marketing items were collected, 59 of which were unique. Among the unique items that showed images of persons (“models”), 70 % showed models appearing to be from racial/ethnic minoritized groups, 86.8 % showed at least one female-presenting model, and 37.5 % showed models appearing to be young adults (18–29 years). Items often had an embedded link/URL (91.5 %) and mentioned topics such as online services (54.2 %; for example, online ordering and tutorials), user experience (49.2 %), social media (44.1 %), and purchasing locations (37.3 %). When examined for their main purpose, items focused on subjects such as store experience (37.7 %), product introduction (18.6 %), and product use (15.3 %).
Conclusions
Our study highlights the importance of better understanding how novel tobacco products are marketed, which can inform policymakers’ regulatory efforts and product authorization decisions.En ligne : https://doi.org/10.1016/j.pmedr.2024.102634 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10543 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Correcting misperceptions about very low nicotine cigarettes for cigarette-only smokers, dual/poly smokers, other tobacco users, and non-tobacco users / Rui Shi (2024)
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Titre : Correcting misperceptions about very low nicotine cigarettes for cigarette-only smokers, dual/poly smokers, other tobacco users, and non-tobacco users Type de document : document électronique Auteurs : Rui Shi, Auteur ; Robert Feldman, Auteur ; Jiaying Liu, Auteur ; Pamela I. Clark, Auteur Editeur : Elsevier Science Direct Année de publication : 2024 Collection : Preventive Medicine Reports, ISSN 2211-3355 num. 46 Importance : 6 p. Présentation : tab. Langues : Anglais (eng) Catégories : [DIVERS] géographie:Amérique:Amérique du Nord:Etats-Unis
[TABAC] chimie du tabac:constituant:alcaloïde:nicotine
[TABAC] étude
[TABAC] prévention:santé
[TABAC] tabagisme:risqueIndex. décimale : TA 4.1 Habitudes tabagiques Résumé : Background
The U.S. Food and Drug Administration authorized the sale and marketing of two very low nicotine cigarettes (VLNC) as modified risk tobacco products. The misperception that VLNC are healthier than regular cigarettes is common. This study explores effective message strategies to inform the public about health risks associated with VLNC use, encourage cigarette smokers to try VLNC, and prevent other tobacco users and non-users from product initiation.
Methods
Following the Reasoned Action approach, a VLNC educational message was developed based on the salient beliefs associated with behavioral intention. The message was tested in an online survey conducted in 2018, where 410 participants were randomly assigned to one of the two message conditions (no-message, VLNC message). Message effects were assessed across four tobacco-use groups (non-tobacco users, cigarette-only smokers, cigarette dual/poly smokers, other tobacco users).
Results
Compared to the no-message control, the VLNC message condition showed lower nicotine risk perception for all participants, lower misbelief in VLNC safety for non-users and cigarette-only smokers, higher belief in VLNC carcinogenicity for other tobacco users, stronger belief in second-hand smoke harm for cigarette dual/poly smokers and other tobacco users, and higher VLNC intention for cigarette-only smokers.
Conclusions
Different messages are needed for different types of tobacco users. Both cigarette smokers and other tobacco users could benefit from messages that acknowledge the non-addictiveness but emphasize the health risks of VLNC. Regulators could consider making physical harm statements a requirement for VLNC packaging and marketing. New strategies need to be explored to inform cigarette dual/poly smokers.En ligne : https://doi.org/10.1016/j.pmedr.2024.102856 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10480 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Dual and poly-nicotine and tobacco use among adolescents in the United States from 2011 to 2022 / Baihui Y. Zhang (2024)
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Titre : Dual and poly-nicotine and tobacco use among adolescents in the United States from 2011 to 2022 Type de document : document électronique Auteurs : Baihui Y. Zhang, Auteur ; Olivia S. Bannon, Auteur ; Daniel Tzu-Hsuan Chen, Auteur ; Filippos T Filippidis, Auteur Editeur : Elsevier Science Direct Année de publication : 2024 Collection : Addictive Behaviors num. 152 Importance : 8 p. Présentation : ill., graph. Langues : Anglais (eng) Catégories : [DIVERS] géographie:Amérique:Amérique du Nord:Etats-Unis
[DIVERS] personne:famille:adolescent
[TABAC] chimie du tabac:constituant:alcaloïde:nicotine
[TABAC] prévention:santé:santé du jeune
[TABAC] tabagisme:tabagisme actif
[PROMOSAN] étude:enquêteIndex. décimale : TA 2.4.1 Enfants et jeunes Résumé : Background
Adolescent nicotine and tobacco product use remains common despite declining smoking rates in the United States, likely due to the emergence of novel products. Concurrent use of multiple products may increase the risk of nicotine dependency and subsequent substance use.
Aim
To identify patterns and trends of dual and poly nicotine and tobacco use among adolescents in the US and explore associations of dual and poly nicotine and tobacco use with sociodemographic factors.
Methods
12 years of annual National Youth Tobacco Survey data (2011–2022) from 242,637 respondents were used to examine prevalence trends of different combinations of nicotine or tobacco product use among adolescents in the US using weighted point estimates for each year. Poisson regression models examined sociodemographic factors associated with different patterns of dual and poly-product use from 2011 to 2022.
Results
Overall, the prevalence of dual (i.e. at least two products) and poly (i.e. at least three products) use decreased between 2011 and 2021 (from 9.5 % to 2.8 % and from 5.1 % to 1.1 %, respectively), but showed signs of increase between 2021 and 2022 (3.7 % for dual and 1.7 % for poly use). The most common combinations included a combustible product with either a novel or noncombustible product. The risk for dual and poly-product use was higher among non-Hispanic Whites, males, and high school students.
Conclusions
Previously declining trends in the prevalence of tobacco/nicotine dual and poly use may have been reversed. Close monitoring and targeted tobacco control policies are essential to tackle multiple product use among adolescents.En ligne : https://doi.org/10.1016/j.addbeh.2024.107970 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10550 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : Genotoxicity of environmental tobacco smoke : a review Type de document : document électronique Auteurs : Kristi Husgafvel-Pursiainen, Auteur Editeur : Elsevier Science Direct Année de publication : 2004 Collection : Mutation Research: Reviews in Mutation Research, ISSN 1388-2139 num. 567 Importance : p.427–445 Langues : Anglais (eng) Catégories : [TABAC] tabagisme:risque:facteur associé:génétique
[TABAC] tabagisme:tabagisme passifIndex. décimale : TA 7.4 Effets du tabagisme passif Résumé : Environmental tobacco smoke (ETS), or second-hand smoke, is a widespread contaminant of indoor air in environments where smoking is not prohibited. It is a significant source of exposure to a large number of substances known to be hazardous to human health. Numerous expert panels have concluded that there is sufficient evidence to classify involuntary smoking (or passive smoking) as carcinogenic to humans. According to the recent evaluation by the International Agency for Research on Cancer, involuntary smoking causes lung cancer in never-smokers with an excess risk in the order of 20% for women and 30% for men. The present paper reviews studies on genotoxicity and related endpoints carried out on ETS since the mid-1980s. The evidence from in vitro studies demonstrates induction of DNA strand breaks, formation of DNA adducts, mutagenicity in bacterial assays and cytogenetic effects. In vivo experiments in rodents have shown that exposure to tobacco smoke, whole-body exposure to mainstream smoke (MS), sidestream smoke (SS), or their mixture, causes DNA single strand breaks, aromatic adducts and oxidative damage to DNA, chromosome aberrations and micronuclei. Genotoxicity of transplacental exposure to ETS has also been reported. Review of human biomarker studies conducted among non-smokers with involuntary exposure to tobacco smoke indicates presence of DNA adducts, urinary metabolites of carcinogens, urinary mutagenicity, SCEs and hypoxanthine-guanine phosphoribosyltransferase (HPRT) gene mutations (in newborns exposed through involuntary smoking of the mother). Studies on human lung cancer from smokers and never-smokers involuntarily exposed to tobacco smoke suggest occurrence of similar kinds of genetic alterations in both groups. In conclusion, these overwhelming data are compatible with the current knowledge on the mechanisms of carcinogenesis of tobacco-related cancers, occurring not only in smokers but with a high biological plausibility also in involuntary smokers.
En ligne : https://doi.org/10.1016/j.mrrev.2004.06.004 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10025 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
High-quality embryos maintain high pregnancy rates in passive smokers but not in active smokers / Avi Ben-Haroush (2011)
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Titre : High-quality embryos maintain high pregnancy rates in passive smokers but not in active smokers Type de document : document électronique Auteurs : Avi Ben-Haroush, Auteur ; Jacob Ashkenazi, Auteur ; Onit Sapir, Auteur ; Haim Pinkas, Auteur ; Benjamin Fisch, Auteur ; Jacob Farhi, Auteur Editeur : Elsevier Science Direct Année de publication : 2011 Collection : Reproductive BioMedicine Online, ISSN 1472-6491 num. 22(1) Importance : p.44-49 Langues : Anglais (eng) Catégories : [TABAC] étude
[TABAC] tabagisme:effet du tabac:altération de la fonction sexuelle:effet sur la fertilité
[TABAC] tabagisme:risque:facteur associé:grossesse
[TABAC] tabagisme:tabagisme actif
[TABAC] tabagisme:tabagisme passifIndex. décimale : TA 3.2.2.7 Grossesse et fœtus Résumé : This study assesses the effect of passive and active smoking on pregnancy rates after IVF with transfer of high-quality embryos. In a cohort study, women attending the IVF unit in 2006–2007 with favourable parameters for pregnancy (<38 years; less than three IVF cycles, transfer of two highest-grade embryos) grouped by smoking status were included. The cohort included 237 patients/cycles: 42 smokers, 195 non-smokers. The clinical pregnancy rate was significantly lower in smokers (35.7% versus 55.4%,P = 0.021, OR = 0.44 (95% CI 0.22–0.89)), even after conditional stratification on covariates (passive smoker, passive or partner smoker, age group). The live-birth rate was lower in smokers (28.6% versus 42.6%), but the difference was not statistically significant(OR = 0.54 (0.26–1.11)). Among non-smokers, there was no difference in pregnancy rate by passive or partner smoking. On logistic regression, variables predicting pregnancy were age <35 years (P = 0.008, OR = 2.58 (1.2–5.2)) and non-smoking (P = 0.003,OR = 3.47 (1.51–7.98)). In conclusion, transfer of high-quality embryos does not overcome the negative effect of active smoking on pregnancy rate in IVF treatment. The endometrium is apparently involved in the mechanism underlying IVF failure in smokers. En ligne : https://doi.org/10.1016/j.rbmo.2010.09.012 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10101 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Multi-endpoint in vitro toxicological assessment of snus and tobacco-free nicotine pouch extracts / Fan Yu (2024)
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Titre : Multi-endpoint in vitro toxicological assessment of snus and tobacco-free nicotine pouch extracts Type de document : document électronique Auteurs : Fan Yu, Auteur ; Emma Bishop, Auteur ; Fabio Miazzi, Auteur Editeur : Elsevier Science Direct Année de publication : 2024 Collection : Mutation Research: Reviews in Mutation Research, ISSN 1388-2139 num. 895 Importance : 10 p. Présentation : ill., graph.; tab. Langues : Anglais (eng) Catégories : [TABAC] chimie du tabac:constituant:alcaloïde:nicotine
[TABAC] chimie du tabac:tabac non fumé:tabac à sucer:snus
[TABAC] étude
[TABAC] tabagisme:effet du tabac
[TABAC] tabagisme:tabagisme actifMots-clés : Pouche de nicotine Index. décimale : TA 1.2 Tabac non fumé Résumé : ‘Modern’ oral tobacco-free nicotine pouches (NPs) are a nicotine containing product similar in appearance and concept to Swedish snus. A three-step approach was taken to analyse the biological effects of NPs and snus extracts in vitro. ToxTracker was used to screen for biomarkers for oxidative stress, cell stress, protein damage and DNA damage. Cytotoxicity, mutagenicity, and genotoxicity were assessed in the following respective assays: Neutral Red Uptake (NRU), Ames and Mouse Lymphoma Assay (MLA). Targeted analysis of phosphorylation signalling and inflammatory markers under non-toxic conditions was used to investigate any potential signalling pathways or inflammatory response. A reference snus (CRP1.1) and four NPs with various flavours and nicotine strengths were assessed. Test article extracts was generated by incubating one pouch in 20 mL of media (specific to each assay) with the inclusion of the pouch material. NP extracts did not induce any cytotoxicity or mutagenic response, genotoxic response was minimal and limited signalling or inflammatory markers were induced. In contrast, CRP1.1 induced a positive response in four toxicological endpoints in the absence of S9: Srxn1 (oxidative stress), Btg2 (cell stress), Ddit3 (protein damage) and Rtkn (DNA damage), and three endpoints in presence of S9: Srxn1, Ddit3 and Rtkn. CRP1.1 was genotoxic when assessed in MLA and activated signalling pathways involved in proliferation and cellular stress and specifically induced phosphorylation of c-JUN, CREB1, p53, p38 MAPK and to a lesser extent AKT1S1, GSK3α/β, ERK1/2 and RSK1 in a dose-dependent manner. CRP 1.1 extracts resulted in the release of several inflammatory mediators including cytokines IL-1α, IL5, IL6, IL8, IL-1RA, MIF and TNF-β, receptor IL-2RA, and growth factors FGF-basic, VEGF and M-CSF. In conclusion these assays contribute to the weight of evidence assessment of the potential comparative health risks of NPs and snus. En ligne : https://doi.org/10.1016/j.mrgentox.2024.503738 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10531 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Quantification of benzo[a]pyrene and other PAHs in the serum and follicular fluid of smokers versus non-smokers / Michael S. Neal (2008)
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Titre : Quantification of benzo[a]pyrene and other PAHs in the serum and follicular fluid of smokers versus non-smokers Type de document : document électronique Auteurs : Michael S. Neal, Auteur ; Jiping Zhu, Auteur ; Warren G. Foster, Auteur Editeur : Elsevier Science Direct Année de publication : 2008 Collection : Reproductive Toxicology num. 25 Importance : p.100-106 Langues : Anglais (eng) Catégories : [TABAC] tabagisme:effet du tabac:altération de la fonction sexuelle:effet sur la fertilité
[TABAC] tabagisme:tabagisme actif:fumeur
[TABAC] tabagisme:tabagisme passif:non-fumeurIndex. décimale : TA 3.2.2.7 Grossesse et fœtus Résumé : Cigarette smoking is a well-established reproductive hazard that has been linked with decreased fertility in both smokers and those exposed to
second hand smoke. The chemical components responsible for the reproductive toxic effects of cigarette smoke are unknown. Moreover, exposure
of reproductive tissues to the chemical constituents of cigarette smoke is largely unknown. Therefore, we measured the levels of benzo[a]pyrene
(B[a]P), and other polycyclic aromatic hydrocarbons (PAH) present in cigarette smoke, in the serum and follicular fluid of women exposed to
mainstream (n = 19) and side stream smoke (n = 7) compared to non-smokers (n = 10). Women exposed to mainstream smoke had significantly
higher levels of B[a]P (1.32 ± 0.68 ng/ml) in their follicular fluid compared to side stream exposed (0.05 ± 0.01 ng/ml) or their non-smoking
(0.03 ± 0.01 ng/ml) counterparts. More importantly we found significantly higher (p < 0.001) levels of B[a]P in the follicular fluid of women
who did not conceive (1.79 ± 0.03 ng/ml) compared to those that achieved a pregnancy (0.08 ± 0.03 ng/ml). Other PAHs known to be present in
cigarette smoke were also detectable in both serum and follicular fluid of study subjects studied but with lower frequency compared to B[a]P and
no differences in serum or follicular fluid levels between the groups could be demonstrated. The important finding that B[a]P reaches the follicular
fluid and the fact that it is found at much higher levels in women who smoke provides further evidence that of the many toxicants present in
cigarette smoke, B[a]P may be a key compound that is central to the documented adverse effects of cigarette smoke on follicular development and
subsequent fertility.En ligne : https://doi.org/10.1016/j.reprotox.2007.10.012 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10106 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Rationale, pharmacology and clinical efficacy of partial agonists of alpha4beta2 nACh receptors for smoking cessation / Hans Rollema (2007)
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Titre : Rationale, pharmacology and clinical efficacy of partial agonists of alpha4beta2 nACh receptors for smoking cessation Type de document : texte imprimé Auteurs : Hans Rollema, Auteur ; Jotham W. Coe, Auteur ; L. K. Chambers, Auteur ; Raymond S. Hurst, Auteur Editeur : Elsevier Science Direct Année de publication : 2007 Collection : Trends in pharmacological sciences num. 28:7 Importance : p. 316-325 Présentation : ill., graph., tab. Langues : Anglais (eng) Catégories : [TABAC] chimie du tabac:constituant:alcaloïde:nicotine:récepteur nicotinique Index. décimale : TA 6.2.3 Approche pharmacologique Résumé : Most smokers repeatedly fail in their attempts to stop smoking because of the addictive nature of the nicotine in tobacco products. Nicotine dependence is probably mediated through the activation of multiple subtypes of neuronal nicotinic acetylcholine receptor (nAChR), among which the mesolimbic alpha(4)beta(2) subtype has a pivotal role. Here, we discuss the rationale for and the design of alpha(4)beta(2) nAChR partial agonists as novel treatments for tobacco addiction. Such agents are expected to exhibit a dual action by sufficiently stimulating alpha(4)beta(2)-nAChR-mediated dopamine release to reduce craving when quitting and by inhibiting nicotine reinforcement when smoking. Potent and selective alpha(4)beta(2) nAChR partial agonists that exhibit dual agonist and antagonist activity in preclinical models can be identified. The validity of this approach is demonstrated by the clinical efficacy of the alpha(4)beta(2) nAChR partial agonist varenicline, which has significantly better quit rates than do other treatments and offers a new option for smoking cessation pharmacotherapy. En ligne : https://doi.org/10.1016/j.tips.2007.05.003 Format de la ressource électronique : PDF, HTML Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=8367 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité TA 005998 TA 6.2.3 ROL R Article/Périodique Bibliothèque FARES Tabac Consultation sur place
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The association between marijuana and e-cigarette use and exercise behavior among adults / Sophie Boutouis (2024)
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Titre : The association between marijuana and e-cigarette use and exercise behavior among adults Type de document : document électronique Auteurs : Sophie Boutouis, Auteur ; Frances Wymbs, Auteur ; Berkeley Franz, Auteur Editeur : Elsevier Science Direct Année de publication : 2024 Collection : Preventive Medicine Reports, ISSN 2211-3355 num. 40 Importance : p. 1-7 Présentation : tab. Langues : Anglais (eng) Catégories : [DIVERS] géographie:Amérique:Amérique du Nord:Etats-Unis
[DIVERS] personne:par âge:adulte
[DIVERS] qualité de vie:activité physique
[TABAC] chimie du tabac:tabac fumé:cigarette
[TABAC] étude
[TABAC] tabagisme:risque:facteur associé:drogue:cannabisIndex. décimale : TA 0.7 Autres drogues Résumé : Background
As the prevalence of marijuana and e-cigarette use among American adults rises and the perceived risk decreases, more information is needed on the potential costs and benefits of marijuana and e-cigarette use, including patterns of exercise. Prior studies have found mixed results, lacked data on types of exercise, and involved only adolescents and young adults. Thus, the current study explored whether marijuana and e-cigarette use are associated with strength training, walking for exercise, or general physical activity among adults in the United States.
Method
2,591 adults from Wave V of the National Longitudinal Study of Adolescent to Adult Health (2016–2018) comprised the sample. Separate one-way analyses of variance (ANOVAs) and post hoc tests examined whether participants’ marijuana and e-cigarette use predicted their exercise, while follow-up analyses of covariance (ANCOVAs) probed significant effects.
Results
Results indicated that participants’ marijuana and e-cigarette use predicted their walking for exercise, with marijuana users walking the highest number of times per week, followed by non-users, e-cigarette users, and dual users. However, this effect only approached significance after controlling for covariates. There were no significant differences in strength training or general exercise between groups.
Conclusion
These findings challenge the stereotype that marijuana and e-cigarette users are less active than non-users, and future research should examine the potential mechanisms of these findings.
En ligne : https://doi.org/10.1016/j.pmedr.2024.102668 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10529 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
A vape condensate collection method for degradant identification and toxicity screening / Yanira Baldovinos (2023)
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Titre : A vape condensate collection method for degradant identification and toxicity screening Type de document : document électronique Auteurs : Yanira Baldovinos, Auteur ; Precious Obiako, Auteur ; Clancy Collom, Auteur ; Christie M. Sayes, Auteur Editeur : Elsevier Science Direct Année de publication : 2023 Collection : Journal of Hazardous Materials Letters num. 5 Importance : 5 p. Présentation : ill., graph. Langues : Anglais (eng) Catégories : [TABAC] chimie du tabac:constituant:additif
[TABAC] chimie du tabac:constituant:additif:agent de saveur
[TABAC] chimie du tabac:substance toxique
[TABAC] chimie du tabac:tabac fumé:cigarette:cigarette électronique
[TABAC] étudeMots-clés : aérosols Index. décimale : TA 1.1.1 Cigarettes (« normales », électroniques, aromatisées,…) Résumé : Since 2007, the market for e-cigarettes has resulted in increasing demand for newer technologies and flavorings contributing to the complexity of these products. As a result, methodologies for e-cigarette aerosol capturing and testing have become a necessity in understanding the toxicities surrounding e-cigarette products. This study tests an alternative aerosol capture method followed by toxicity testing of the sample collected on a lung in vitro model. En ligne : https://doi.org/10.1016/j.hazl.2023.100099 Format de la ressource électronique : Article en ligne Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=10558 Aucun avis, veuillez vous identifier pour ajouter le vôtre !