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Auteur Jon O. Ebbert |
Documents disponibles écrits par cet auteur (6)
Ajouter le résultat dans votre panier Affiner la rechercheClinical utility of varenicline for smokers with medical and psychiatric comorbidity / Jon O. Ebbert (2009)
Titre : Clinical utility of varenicline for smokers with medical and psychiatric comorbidity Type de document : texte imprimé Auteurs : Jon O. Ebbert, Auteur ; Kirk D Wyatt, Auteur ; Michael V. Burke, Auteur ; J. Taylor Hays, Auteur ; Ali Zirakzadeh, Auteur Editeur : Dove Medical Press Année de publication : 2009 Collection : International journal of Chronic Obstructive Pulmonary Disease, ISSN 1178-2005 num. 4 Importance : p. 421-430 Présentation : tab. Langues : Anglais (eng) Catégories : [DIVERS] discipline médicale, paramédicale et scientifique:médecine:médecine spécialisée:psychiatrie
[TABAC] sevrage tabagique:méthode de sevrage:méthode individuelle:approche pharmacologique:varénicline
[TABAC] tabagisme:pathologie:pathologie respiratoire:broncho-pneumopathie chronique obstructiveIndex. décimale : TA 6.2.3.2 Autres produits Résumé : Chronic obstructive pulmonary disease (COPD) is a costly and deadly disease afflicting an estimated 210 million people and accounting for 5% of all global deaths. Exposure to cigarette smoke is the greatest risk factor for COPD in the developed world. Smoking cessation improves respiratory symptoms and lung function and reduces mortality among patients with COPD. Cigarette smokers with COPD and other co-morbid conditions such as cardiovascular disease and psychiatric illnesses should receive comprehensive tobacco treatment interventions incorporating efficacious pharmacotherapies. Varenicline, an alpha(4)beta(2) nicotinic acetylcholine receptor partial agonist, is the newest and most effective drug currently available to promote smoking cessation. In conjunction with behavioral interventions and clinical monitoring for potential side effects, varenicline offers great hope for reducing smoking-attributable death and disability. Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=8134 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : Combination treatment with varenicline and nicotine replacement therapy Type de document : texte imprimé Auteurs : Jon O. Ebbert, Auteur ; Michael V. Burke, Auteur ; Richard D. Hurt, Auteur Editeur : Oxford University Press Année de publication : 2009 Collection : Nicotine and Tobacco Research num. Vol 11, n. 5 Importance : p. 572-576 Langues : Anglais (eng) Catégories : [TABAC] étude
[TABAC] sevrage tabagique:méthode de sevrage:méthode individuelle:approche pharmacologique:substitution nicotinique
[TABAC] sevrage tabagique:méthode de sevrage:méthode individuelle:approche pharmacologique:varéniclineIndex. décimale : TA 6.2.3.1.4 Autres substituts nicotiniques Résumé : Abstract
INTRODUCTION:
A paucity of data exists regarding the safety and effectiveness of combination treatment with varenicline and nicotine replacement therapy (NRT).
METHODS:
We reviewed the clinical experience of two groups of cigarette smokers enrolled in a residential tobacco treatment program: (a) patients receiving combination treatment with varenicline and NRT (N = 104) and (b) usual-care patients receiving treatment before the release of varenicline (N = 135).
RESULTS:
Demographic characteristics were similar between the two groups. Among smokers receiving varenicline and NRT, 71% used the nicotine patch with a mean dose of 32 mg/day (SD = 14) and 73% used at least two types of NRT. Adverse events were experienced by 39% (95% CI = 31%-49%) of patients receiving varenicline and NRT and by 59% (95% CI = 51%-67%) of usual-care patients during the residential program. A total of five patients (5%) discontinued varenicline due to adverse events, compared with one patient in the usual-care group. We did not observe a significant difference in the 30-day point prevalence smoking abstinence rate at 6 months between patients treated with varenicline and NRT (54%; 95% CI = 44%-64%) and usual-care patients (59%; 95% CI = 50%-66%).
DISCUSSION:
Our findings suggest that combination therapy with varenicline and NRT is safe and well tolerated among patients in a residential tobacco treatment program.Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=7950 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité TA 005491 TA 6.2.3.1.4 EBB C Article/Périodique Bibliothèque FARES Tabac Consultation sur place
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Titre : Pharmacological interventions for the treatment of smokeless tobacco use Type de document : texte imprimé Auteurs : Jon O. Ebbert, Auteur ; Karl Fagerström, Auteur Editeur : Adis International Année de publication : 2012 Collection : CNS Drugs, ISSN 1172-7047 num. Vol. 26 Importance : 10 p. Présentation : tab. Langues : Anglais (eng) Catégories : [TABAC] sevrage tabagique:méthode de sevrage:méthode individuelle:approche pharmacologique:bupropion
[TABAC] sevrage tabagique:méthode de sevrage:méthode individuelle:approche pharmacologique:substitution nicotinique
[TABAC] sevrage tabagique:méthode de sevrage:méthode individuelle:approche pharmacologique:varéniclineIndex. décimale : TA 6.2.3 Approche pharmacologique Résumé : Smokeless tobacco (SLT) is used in a variety of forms throughout the world. Long-term SLT use is associated with adverse health consequences. Effective pharmacotherapies are needed to treat SLT users who want to achieve tobacco abstinence. In the current review, we discuss the pharmacological interventions identified in a recent meta-analysis of interventions for SLT users, with inclusion of additional articles identified by searching PubMed up to August 2011. Nicotine replacement therapy (NRT) has been demonstrated to increase short-term tobacco abstinence rates and to alleviate craving and withdrawal symptoms among SLT users trying to quit. Bupropion sustained release has been shown to decrease craving and attenuate post-cessation weight gain among SLT users trying to quit. Varenicline is the only available medication demonstrated to increase long-term (≥6 months) tobacco abstinence rates among SLT users. Overall, findings from studies investigating pharmacotherapies for SLT users have been relatively disappointing. SLT reduction interventions may hold some promise for increasing abstinence rates among SLT users not interested in quitting. Additional investigations of higher dose NRT and combination pharmacotherapy are needed to advance the treatment of SLT users. Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=7959 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité TA 005500 TA 6.2.3 EBB P Article/Périodique Bibliothèque FARES Tabac Consultation sur place
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Titre : Varenicline and bupropion sustained-release combination therapy for smoking cessation Type de document : texte imprimé Auteurs : Jon O. Ebbert, Auteur ; Ivana T. Croghan, Auteur ; Amit Sood, Auteur Editeur : Oxford University Press Année de publication : 2009 Collection : Nicotine and Tobacco Research num. Vol 11, n.3 Importance : p. 234-239 Présentation : tad., graph. Langues : Anglais (eng) Catégories : [TABAC] étude
[TABAC] sevrage tabagique:méthode de sevrage:méthode individuelle:approche pharmacologique:bupropion
[TABAC] sevrage tabagique:méthode de sevrage:méthode individuelle:approche pharmacologique:varéniclineIndex. décimale : TA 6.2.3.1.4 Autres substituts nicotiniques Résumé : Abstract
INTRODUCTION:
Varenicline and bupropion sustained release (SR) are both safe and effective for the treatment of tobacco dependence and have different mechanisms of action. Combination pharmacotherapy with these agents may increase long-term smoking abstinence rates above what is observed with single-agent therapy.
METHODS:
We enrolled cigarettes smokers in an open-label, one-arm, Phase II clinical trial to obtain preliminary data on the potential effectiveness and safety of combination therapy with varenicline and bupropion SR for the treatment of tobacco dependence. Eligible subjects received varenicline titrated to 1.0 mg by mouth twice daily and bupropion SR titrated to 150 mg by mouth twice daily for a total of 12 weeks along with behavioral therapy. Self-reported smoking abstinence was biochemically confirmed with expired carbon monoxide. A total of 38 smokers with a mean age of 49.1 years (SD = 12.4) who smoked an average of 19.9 cigarettes/day (SD = 7.8) for 30 years (SD = 12.3) were enrolled.
RESULTS:
Seven-day point-prevalent smoking abstinence rates were 71% (95% CI = 54%-85%) at 3 months and 58% (95% CI = 41%-74%) at 6 months. Mean weight change during the medication phase among smoking-abstinent subjects was 1.6 kg (SD = 2.4). For both medications, 74% of subjects took at least 90% of the prescribed doses. The most common side effects were sleep disturbance (26%) and nausea (24%). No increase in depressive symptoms was observed, and no subjects reported suicidal ideation.
DISCUSSION:
Combination therapy with varenicline and bupropion SR may be effective for increasing smoking abstinence rates above that observed with monotherapy.Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=7947 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité TA 005488 TA 6.2.3.1.4 EBB V Article/Périodique Bibliothèque FARES Tabac Consultation sur place
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Titre : Varenicline for tobacco dependence Type de document : texte imprimé Auteurs : J. Taylor Hays, Auteur ; Jon O. Ebbert, Auteur Editeur : Massachusetts Medical Society Année de publication : 2008 Collection : New England Journal of Medicine num. Vol 259 Importance : p. 2018-2024 Présentation : ill., tab. Langues : Anglais (eng) Catégories : [TABAC] sevrage tabagique:méthode de sevrage:méthode individuelle:approche pharmacologique:varénicline Index. décimale : TA 6.2.3.1.4 Autres substituts nicotiniques En ligne : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959114/ Format de la ressource électronique : HTML Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=7952 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
Titre : Waking a Sleeping Giant : The Tobacco Industry’s Response to the Polonium-210 Issue Type de document : texte imprimé Auteurs : Monique E. Muggli, Auteur ; Jon O. Ebbert, Auteur ; Channing Robertson, Auteur ; Richard D. Hurt, Auteur Editeur : Alpha Press Année de publication : 01/09/2008 Collection : American Journal of Public Health num. 98 (9) Importance : p.1643-1650 Note générale : Dans la bibliothèque virtuelle (articles scientifiques) Catégories : [TABAC] chimie du tabac:constituant:additif
[TABAC] chimie du tabac:fumée:polonium
[TABAC] chimie du tabac:substance toxiqueIndex. décimale : TA 1.4 Additifs Résumé : The major tobacco manufacturers discovered that polonium was part of tobacco and tobacco smoke more than 40 years ago and attempted, but failed, to remove this radioactive substance from their products. Internal tobacco industry documents reveal that the companies suppressed publication of their own internal research to avoid heightening the public’s awareness of radioactivity in cigarettes. Tobacco companies continue to minimize their knowledge about polonium- 210 in cigarettes in smoking and health litigation. Cigarette packs should carry a radiation-exposure warning label. En ligne : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2509609/ Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=1444 Aucun avis, veuillez vous identifier pour ajouter le vôtre !
